Hyperoxia Provokes Time- and Dose-Dependent Gut Injury and Endotoxemia and Alters Gut Microbiome and Transcriptome in Mice

Hyperoxia Provokes Time- and Dose-Dependent Gut Injury and Endotoxemia and Alters Gut Microbiome and Transcriptome in Mice

Background: Oxygen therapy usually exposes patients to hyperoxia, which induces injuries in the lung, the heart, and the brain. The gut and its microbiome play key roles in critical illnesses, but the impact of hyperoxia on the gut and its microbiome remains not very clear. We clarified the time- an...

Full description

Saved in:
Bibliographic Details
Main Authors: Yunhang Li, Yuanfa Tao, Jingyu Xu, Yihuai He, Wen Zhang, Zhigang Jiang, Ying He, Houmei Liu, Miao Chen, Wei Zhang, Zhouxiong Xing
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
oxygen therapy
hyperoxia
gut injury
gut microbiome
Enterobacteriaceae
toll-like receptor-4
Medicine (General)
R5-920
Online Access:https://doaj.org/article/c7946cd3a9de4b769e60609d39c2a6c2
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/c7946cd3a9de4b769e60609d39c2a6c2

Similar Items