Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1

The meiotic telomere complex (MAJIN, TERB1, TERB2) tethers telomere ends to the nuclear envelope. Here the authors present the crystal structure of human MAJIN-TERB2 and combine biophysical approaches and structured illumination microscopy analysis of mouse meiotic chromosomes to characterize the mo...

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Autores principales:	James M. Dunce, Amy E. Milburn, Manickam Gurusaran, Irene da Cruz, Lee T. Sen, Ricardo Benavente, Owen R. Davies
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c795be0929864372986ddb798eaeecbf
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spelling	oai:doaj.org-article:c795be0929864372986ddb798eaeecbf2021-12-02T14:40:31ZStructural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB110.1038/s41467-018-07794-72041-1723https://doaj.org/article/c795be0929864372986ddb798eaeecbf2018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07794-7https://doaj.org/toc/2041-1723The meiotic telomere complex (MAJIN, TERB1, TERB2) tethers telomere ends to the nuclear envelope. Here the authors present the crystal structure of human MAJIN-TERB2 and combine biophysical approaches and structured illumination microscopy analysis of mouse meiotic chromosomes to characterize the molecular architecture of the wider MAJIN-TERB2-TERB1 complex and its interactions with TRF1.James M. DunceAmy E. MilburnManickam GurusaranIrene da CruzLee T. SenRicardo BenaventeOwen R. DaviesNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q James M. Dunce Amy E. Milburn Manickam Gurusaran Irene da Cruz Lee T. Sen Ricardo Benavente Owen R. Davies Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1
description	The meiotic telomere complex (MAJIN, TERB1, TERB2) tethers telomere ends to the nuclear envelope. Here the authors present the crystal structure of human MAJIN-TERB2 and combine biophysical approaches and structured illumination microscopy analysis of mouse meiotic chromosomes to characterize the molecular architecture of the wider MAJIN-TERB2-TERB1 complex and its interactions with TRF1.
format	article
author	James M. Dunce Amy E. Milburn Manickam Gurusaran Irene da Cruz Lee T. Sen Ricardo Benavente Owen R. Davies
author_facet	James M. Dunce Amy E. Milburn Manickam Gurusaran Irene da Cruz Lee T. Sen Ricardo Benavente Owen R. Davies
author_sort	James M. Dunce
title	Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1
title_short	Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1
title_full	Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1
title_fullStr	Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1
title_full_unstemmed	Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1
title_sort	structural basis of meiotic telomere attachment to the nuclear envelope by majin-terb2-terb1
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c795be0929864372986ddb798eaeecbf
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Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1

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