Ca<sup>2+</sup>/Sr<sup>2+</sup> Selectivity in Calcium-Sensing Receptor (CaSR): Implications for Strontium’s Anti-Osteoporosis Effect
The extracellular calcium-sensing receptor (CaSR) controls vital bone cell functions such as cell growth, differentiation and apoptosis. The binding of the native agonist (Ca<sup>2+</sup>) to CaSR activates the receptor, which undergoes structural changes that trigger a cascade of events...
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Autores principales: | Diana Cheshmedzhieva, Sonia Ilieva, Eugene A. Permyakov, Sergei E. Permyakov, Todor Dudev |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c7a26232e69549ffba8a8a9ce092b027 |
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