Hypothalamic GPR40 signaling activated by free long chain fatty acids suppresses CFA-induced inflammatory chronic pain.

GPR40 has been reported to be activated by long-chain fatty acids, such as docosahexaenoic acid (DHA). However, reports studying functional role of GPR40 in the brain are lacking. The present study focused on the relationship between pain regulation and GPR40, investigating the functional roles of h...

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Autores principales: Kazuo Nakamoto, Takashi Nishinaka, Naoya Sato, Mitsumasa Mankura, Yutaka Koyama, Fumiyo Kasuya, Shogo Tokuyama
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/c7b84b5003f446ffb110bdf95fb9943c
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