AGO1 homeostasis involves differential production of 21-nt and 22-nt miR168 species by MIR168a and MIR168b.
<h4>Background</h4>AGO1 associates with microRNAs (miRNAs) and regulates mRNAs through cleavage and translational repression. AGO1 homeostasis entails DCL1-dependent production of miR168 from MIR168a and MIR168b transcripts, post-transcriptional stabilization of miR168 by AGO1, and AGO1-...
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| Format: | article |
| Language: | EN |
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Public Library of Science (PLoS)
2009
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| Online Access: | https://doaj.org/article/c7b938bf16c345b1a5dcca673fb121d9 |
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