A role for GABA in the modulation of striatal and hippocampal systems under stress

Using fMRI and MRS measurements from healthy, young adults, Dolfen et al examined the effects of motor learning and stress on striatal and hippocampal GABA levels, as well as effects on neural correlates of learning. They demonstrated that stress modulated the link between striatal GABA levels and f...

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Autores principales:	Nina Dolfen, Menno P. Veldman, Mareike A. Gann, Andreas von Leupoldt, Nicolaas A. J. Puts, Richard A. E. Edden, Mark Mikkelsen, Stephan Swinnen, Lars Schwabe, Geneviève Albouy, Bradley R. King
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/c7ba326ee68549eea620b289123c911c
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spelling	oai:doaj.org-article:c7ba326ee68549eea620b289123c911c2021-12-02T15:28:56ZA role for GABA in the modulation of striatal and hippocampal systems under stress10.1038/s42003-021-02535-x2399-3642https://doaj.org/article/c7ba326ee68549eea620b289123c911c2021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02535-xhttps://doaj.org/toc/2399-3642Using fMRI and MRS measurements from healthy, young adults, Dolfen et al examined the effects of motor learning and stress on striatal and hippocampal GABA levels, as well as effects on neural correlates of learning. They demonstrated that stress modulated the link between striatal GABA levels and functional plasticity in the hippocampus and striatum, which reveals a role for GABA in the stress-induced modulation of these systems.Nina DolfenMenno P. VeldmanMareike A. GannAndreas von LeupoldtNicolaas A. J. PutsRichard A. E. EddenMark MikkelsenStephan SwinnenLars SchwabeGeneviève AlbouyBradley R. KingNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Nina Dolfen Menno P. Veldman Mareike A. Gann Andreas von Leupoldt Nicolaas A. J. Puts Richard A. E. Edden Mark Mikkelsen Stephan Swinnen Lars Schwabe Geneviève Albouy Bradley R. King A role for GABA in the modulation of striatal and hippocampal systems under stress
description	Using fMRI and MRS measurements from healthy, young adults, Dolfen et al examined the effects of motor learning and stress on striatal and hippocampal GABA levels, as well as effects on neural correlates of learning. They demonstrated that stress modulated the link between striatal GABA levels and functional plasticity in the hippocampus and striatum, which reveals a role for GABA in the stress-induced modulation of these systems.
format	article
author	Nina Dolfen Menno P. Veldman Mareike A. Gann Andreas von Leupoldt Nicolaas A. J. Puts Richard A. E. Edden Mark Mikkelsen Stephan Swinnen Lars Schwabe Geneviève Albouy Bradley R. King
author_facet	Nina Dolfen Menno P. Veldman Mareike A. Gann Andreas von Leupoldt Nicolaas A. J. Puts Richard A. E. Edden Mark Mikkelsen Stephan Swinnen Lars Schwabe Geneviève Albouy Bradley R. King
author_sort	Nina Dolfen
title	A role for GABA in the modulation of striatal and hippocampal systems under stress
title_short	A role for GABA in the modulation of striatal and hippocampal systems under stress
title_full	A role for GABA in the modulation of striatal and hippocampal systems under stress
title_fullStr	A role for GABA in the modulation of striatal and hippocampal systems under stress
title_full_unstemmed	A role for GABA in the modulation of striatal and hippocampal systems under stress
title_sort	role for gaba in the modulation of striatal and hippocampal systems under stress
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c7ba326ee68549eea620b289123c911c
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A role for GABA in the modulation of striatal and hippocampal systems under stress

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