Mesenchymal stem cells as a platform for research on traditional medicine

The translation of Traditional Medicines (TMs) such as Ayurveda, and Traditional Chinese Medicine into clinical practice remains obstructed due to lack of scientific evidence by means of safety, quality, standardization, clinical efficacy, and mode of action. These limitations can be attributed to t...

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Autores principales:	Ramesh Bhonde, Avinash Sanap, Kalpana Joshi
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Evidence-based traditional medicines Ayurveda Mesenchymal stem cells Miscellaneous systems and treatments RZ409.7-999
Acceso en línea:	https://doaj.org/article/c7c26eba283f4e66ab944ced5b3bba37
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spelling	oai:doaj.org-article:c7c26eba283f4e66ab944ced5b3bba372021-12-02T04:59:23ZMesenchymal stem cells as a platform for research on traditional medicine0975-947610.1016/j.jaim.2021.08.012https://doaj.org/article/c7c26eba283f4e66ab944ced5b3bba372021-10-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S0975947621001881https://doaj.org/toc/0975-9476The translation of Traditional Medicines (TMs) such as Ayurveda, and Traditional Chinese Medicine into clinical practice remains obstructed due to lack of scientific evidence by means of safety, quality, standardization, clinical efficacy, and mode of action. These limitations can be attributed to the lack of synonymous in vitro models which reflect in vivo features. Human mesenchymal stem cells (hMSCs) have emerged as an efficient cell source for regenerative medicine and tissue engineering. In this review, the authors discuss how hMSCs can be used as an in vitro platform to screen herbs described in TMs using modern methods such as evaluation of its potential, safety, quality, mode of action, etc. Integration of traditional knowledge systems like Ayurveda and hMSCs as a platform to screen and study TMs using modern tools will effectively increase the validity of TMs as evidence-based medicine.Ramesh BhondeAvinash SanapKalpana JoshiElsevierarticleEvidence-based traditional medicinesAyurvedaMesenchymal stem cellsMiscellaneous systems and treatmentsRZ409.7-999ENJournal of Ayurveda and Integrative Medicine, Vol 12, Iss 4, Pp 722-728 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Evidence-based traditional medicines Ayurveda Mesenchymal stem cells Miscellaneous systems and treatments RZ409.7-999
spellingShingle	Evidence-based traditional medicines Ayurveda Mesenchymal stem cells Miscellaneous systems and treatments RZ409.7-999 Ramesh Bhonde Avinash Sanap Kalpana Joshi Mesenchymal stem cells as a platform for research on traditional medicine
description	The translation of Traditional Medicines (TMs) such as Ayurveda, and Traditional Chinese Medicine into clinical practice remains obstructed due to lack of scientific evidence by means of safety, quality, standardization, clinical efficacy, and mode of action. These limitations can be attributed to the lack of synonymous in vitro models which reflect in vivo features. Human mesenchymal stem cells (hMSCs) have emerged as an efficient cell source for regenerative medicine and tissue engineering. In this review, the authors discuss how hMSCs can be used as an in vitro platform to screen herbs described in TMs using modern methods such as evaluation of its potential, safety, quality, mode of action, etc. Integration of traditional knowledge systems like Ayurveda and hMSCs as a platform to screen and study TMs using modern tools will effectively increase the validity of TMs as evidence-based medicine.
format	article
author	Ramesh Bhonde Avinash Sanap Kalpana Joshi
author_facet	Ramesh Bhonde Avinash Sanap Kalpana Joshi
author_sort	Ramesh Bhonde
title	Mesenchymal stem cells as a platform for research on traditional medicine
title_short	Mesenchymal stem cells as a platform for research on traditional medicine
title_full	Mesenchymal stem cells as a platform for research on traditional medicine
title_fullStr	Mesenchymal stem cells as a platform for research on traditional medicine
title_full_unstemmed	Mesenchymal stem cells as a platform for research on traditional medicine
title_sort	mesenchymal stem cells as a platform for research on traditional medicine
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/c7c26eba283f4e66ab944ced5b3bba37
work_keys_str_mv	AT rameshbhonde mesenchymalstemcellsasaplatformforresearchontraditionalmedicine AT avinashsanap mesenchymalstemcellsasaplatformforresearchontraditionalmedicine AT kalpanajoshi mesenchymalstemcellsasaplatformforresearchontraditionalmedicine
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Mesenchymal stem cells as a platform for research on traditional medicine

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