An apicobasal gradient of Rac activity determines protrusion form and position

An apicobasal gradient of Rac activity determines protrusion form and position

Polarized epithelial cells must correctly position a wide range of subcellular structures. Here the authors demonstrate an apicobasal gradient of Rac GTPase activity, which is maintained by polarity proteins inDrosophilaepithelial sheets, and is required to maintain actin-dependent protrusion form a...

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Autores principales: Africa Couto, Natalie Ann Mack, Lucrezia Favia, Marios Georgiou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c7c769ce4a7d4348848c5188950062a1
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spelling oai:doaj.org-article:c7c769ce4a7d4348848c5188950062a12021-12-02T14:42:39ZAn apicobasal gradient of Rac activity determines protrusion form and position10.1038/ncomms153852041-1723https://doaj.org/article/c7c769ce4a7d4348848c5188950062a12017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15385https://doaj.org/toc/2041-1723Polarized epithelial cells must correctly position a wide range of subcellular structures. Here the authors demonstrate an apicobasal gradient of Rac GTPase activity, which is maintained by polarity proteins inDrosophilaepithelial sheets, and is required to maintain actin-dependent protrusion form and position.Africa CoutoNatalie Ann MackLucrezia FaviaMarios GeorgiouNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Africa Couto
Natalie Ann Mack
Lucrezia Favia
Marios Georgiou
An apicobasal gradient of Rac activity determines protrusion form and position
description Polarized epithelial cells must correctly position a wide range of subcellular structures. Here the authors demonstrate an apicobasal gradient of Rac GTPase activity, which is maintained by polarity proteins inDrosophilaepithelial sheets, and is required to maintain actin-dependent protrusion form and position.
format article
author Africa Couto
Natalie Ann Mack
Lucrezia Favia
Marios Georgiou
author_facet Africa Couto
Natalie Ann Mack
Lucrezia Favia
Marios Georgiou
author_sort Africa Couto
title An apicobasal gradient of Rac activity determines protrusion form and position
title_short An apicobasal gradient of Rac activity determines protrusion form and position
title_full An apicobasal gradient of Rac activity determines protrusion form and position
title_fullStr An apicobasal gradient of Rac activity determines protrusion form and position
title_full_unstemmed An apicobasal gradient of Rac activity determines protrusion form and position
title_sort apicobasal gradient of rac activity determines protrusion form and position
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/c7c769ce4a7d4348848c5188950062a1
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