An apicobasal gradient of Rac activity determines protrusion form and position

Polarized epithelial cells must correctly position a wide range of subcellular structures. Here the authors demonstrate an apicobasal gradient of Rac GTPase activity, which is maintained by polarity proteins inDrosophilaepithelial sheets, and is required to maintain actin-dependent protrusion form a...

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Bibliographic Details
Main Authors: Africa Couto, Natalie Ann Mack, Lucrezia Favia, Marios Georgiou
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/c7c769ce4a7d4348848c5188950062a1
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