Lidocaine versus Dexmedetomidine as an adjuvant to General Anesthesia for patients undergoing Elective Abdominopelvic Surgeries

Background: The fundamental impact of dexmedetomidine on the cardiovascular framework obstruction is the extra component of narcotic saving impact. Similarly, fundamental Lidocaine that is utilized as a consistent mixture during the operation period has pain-relieving, antihyperalgesic, and calming...

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Autor principal:	Sameh Seyam
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2020
Materias:	abdominopelvic surgeries general anesthesia dexmedetomidine lidocaine adjuvant Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/c7cf5909a3a94afdbd94779681edc5c7
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spelling	oai:doaj.org-article:c7cf5909a3a94afdbd94779681edc5c72021-12-02T15:22:18ZLidocaine versus Dexmedetomidine as an adjuvant to General Anesthesia for patients undergoing Elective Abdominopelvic Surgeries2636-41742682-378010.21608/ijma.2020.23550.1096https://doaj.org/article/c7cf5909a3a94afdbd94779681edc5c72020-04-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_78929_947e9e1b8d5a7220b30cc94b28246e68.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: The fundamental impact of dexmedetomidine on the cardiovascular framework obstruction is the extra component of narcotic saving impact. Similarly, fundamental Lidocaine that is utilized as a consistent mixture during the operation period has pain-relieving, antihyperalgesic, and calming chattels. Aim of the work: To analyze the effectiveness of lidocaine given intravenously with that of dexmedetomidine as an adjuvant to general anesthesia for candidates listed for elective abdominal and pelvic surgery. Patients and Methods:120 patients of both sexes undergoing elective pelviabdominal procedures were enlisted. Patients were assigned randomly to one of three equal groups: group 1 received a loading lidocaine 1.5 mg/kg, followed by an infusion of 2 mg/kg/h, group 2 received a loading dexmedetomidine1 μg/kg, followed by 0.5 μg/kg/h, and group 3 received normal saline 0.9% in the same design as previous medicines. Hemodynamics, consumption of anesthetic agents, induction and recovery times, and time to the first postoperative analgesic request were reported. Results: The hemodynamics after intubation and in the next records, were significantly lower in groups 1 and 2 when compared with group 3 with no significant variance between groups 2 and 1. The induction dosage of propofol, mean end-tidal sevoflurane concentration and the consumption of fentanyl intraoperatively were significantly lower in group 2 when compared with group 1. The time through anesthesia induction was significantly lower in group 1 and 2 when compared with group 3. The time to the first analgesic demand postoperatively was significantly longer in group 2 when compared with group 1. Conclusion: Both lidocaine and dexmedetomidine could be a beneficial adjuvant to general anesthesia. Though, dexmedetomidine has a much economic effect on intraoperative anesthetic agent consumption and more extended time to the first postoperative analgesic request.Sameh SeyamAl-Azhar University, Faculty of Medicine (Damietta)articleabdominopelvic surgeriesgeneral anesthesiadexmedetomidinelidocaineadjuvantMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 2, Iss 2, Pp 427-435 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	abdominopelvic surgeries general anesthesia dexmedetomidine lidocaine adjuvant Medicine (General) R5-920
spellingShingle	abdominopelvic surgeries general anesthesia dexmedetomidine lidocaine adjuvant Medicine (General) R5-920 Sameh Seyam Lidocaine versus Dexmedetomidine as an adjuvant to General Anesthesia for patients undergoing Elective Abdominopelvic Surgeries
description	Background: The fundamental impact of dexmedetomidine on the cardiovascular framework obstruction is the extra component of narcotic saving impact. Similarly, fundamental Lidocaine that is utilized as a consistent mixture during the operation period has pain-relieving, antihyperalgesic, and calming chattels. Aim of the work: To analyze the effectiveness of lidocaine given intravenously with that of dexmedetomidine as an adjuvant to general anesthesia for candidates listed for elective abdominal and pelvic surgery. Patients and Methods:120 patients of both sexes undergoing elective pelviabdominal procedures were enlisted. Patients were assigned randomly to one of three equal groups: group 1 received a loading lidocaine 1.5 mg/kg, followed by an infusion of 2 mg/kg/h, group 2 received a loading dexmedetomidine1 μg/kg, followed by 0.5 μg/kg/h, and group 3 received normal saline 0.9% in the same design as previous medicines. Hemodynamics, consumption of anesthetic agents, induction and recovery times, and time to the first postoperative analgesic request were reported. Results: The hemodynamics after intubation and in the next records, were significantly lower in groups 1 and 2 when compared with group 3 with no significant variance between groups 2 and 1. The induction dosage of propofol, mean end-tidal sevoflurane concentration and the consumption of fentanyl intraoperatively were significantly lower in group 2 when compared with group 1. The time through anesthesia induction was significantly lower in group 1 and 2 when compared with group 3. The time to the first analgesic demand postoperatively was significantly longer in group 2 when compared with group 1. Conclusion: Both lidocaine and dexmedetomidine could be a beneficial adjuvant to general anesthesia. Though, dexmedetomidine has a much economic effect on intraoperative anesthetic agent consumption and more extended time to the first postoperative analgesic request.
format	article
author	Sameh Seyam
author_facet	Sameh Seyam
author_sort	Sameh Seyam
title	Lidocaine versus Dexmedetomidine as an adjuvant to General Anesthesia for patients undergoing Elective Abdominopelvic Surgeries
title_short	Lidocaine versus Dexmedetomidine as an adjuvant to General Anesthesia for patients undergoing Elective Abdominopelvic Surgeries
title_full	Lidocaine versus Dexmedetomidine as an adjuvant to General Anesthesia for patients undergoing Elective Abdominopelvic Surgeries
title_fullStr	Lidocaine versus Dexmedetomidine as an adjuvant to General Anesthesia for patients undergoing Elective Abdominopelvic Surgeries
title_full_unstemmed	Lidocaine versus Dexmedetomidine as an adjuvant to General Anesthesia for patients undergoing Elective Abdominopelvic Surgeries
title_sort	lidocaine versus dexmedetomidine as an adjuvant to general anesthesia for patients undergoing elective abdominopelvic surgeries
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2020
url	https://doaj.org/article/c7cf5909a3a94afdbd94779681edc5c7
work_keys_str_mv	AT samehseyam lidocaineversusdexmedetomidineasanadjuvanttogeneralanesthesiaforpatientsundergoingelectiveabdominopelvicsurgeries
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Lidocaine versus Dexmedetomidine as an adjuvant to General Anesthesia for patients undergoing Elective Abdominopelvic Surgeries

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