Investigating the structural impacts of I64T and P311S mutations in APE1-DNA complex: a molecular dynamics approach.
<h4>Background</h4>Elucidating the molecular dynamic behavior of Protein-DNA complex upon mutation is crucial in current genomics. Molecular dynamics approach reveals the changes on incorporation of variants that dictate the structure and function of Protein-DNA complexes. Deleterious mu...
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Autores principales: | C George Priya Doss, N Nagasundaram |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/c7d0743bc3d840ad9340024731ceb224 |
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