Investigating the structural impacts of I64T and P311S mutations in APE1-DNA complex: a molecular dynamics approach.

<h4>Background</h4>Elucidating the molecular dynamic behavior of Protein-DNA complex upon mutation is crucial in current genomics. Molecular dynamics approach reveals the changes on incorporation of variants that dictate the structure and function of Protein-DNA complexes. Deleterious mu...

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Autores principales: C George Priya Doss, N Nagasundaram
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/c7d0743bc3d840ad9340024731ceb224
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