The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate

Neutrophil extracellular traps (NETs), composed of DNA and proteases, contribute to the innate immune response by capturing pathogens. Here, Chang et al. identify a NET-degrading DNase in Plasmodiumparasites and show that immunization with this protein provides protective immunity in a malaria mouse...

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Autores principales:	Zhiguang Chang, Ning Jiang, Yuanyuan Zhang, Huijun Lu, Jigang Yin, Mats Wahlgren, Xunjia Cheng, Yaming Cao, Qijun Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c7e8d6a556d440b9b0c2ceedd465c7f4
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spelling	oai:doaj.org-article:c7e8d6a556d440b9b0c2ceedd465c7f42021-12-02T17:32:51ZThe TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate10.1038/ncomms115372041-1723https://doaj.org/article/c7e8d6a556d440b9b0c2ceedd465c7f42016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11537https://doaj.org/toc/2041-1723Neutrophil extracellular traps (NETs), composed of DNA and proteases, contribute to the innate immune response by capturing pathogens. Here, Chang et al. identify a NET-degrading DNase in Plasmodiumparasites and show that immunization with this protein provides protective immunity in a malaria mouse model.Zhiguang ChangNing JiangYuanyuan ZhangHuijun LuJigang YinMats WahlgrenXunjia ChengYaming CaoQijun ChenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhiguang Chang Ning Jiang Yuanyuan Zhang Huijun Lu Jigang Yin Mats Wahlgren Xunjia Cheng Yaming Cao Qijun Chen The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate
description	Neutrophil extracellular traps (NETs), composed of DNA and proteases, contribute to the innate immune response by capturing pathogens. Here, Chang et al. identify a NET-degrading DNase in Plasmodiumparasites and show that immunization with this protein provides protective immunity in a malaria mouse model.
format	article
author	Zhiguang Chang Ning Jiang Yuanyuan Zhang Huijun Lu Jigang Yin Mats Wahlgren Xunjia Cheng Yaming Cao Qijun Chen
author_facet	Zhiguang Chang Ning Jiang Yuanyuan Zhang Huijun Lu Jigang Yin Mats Wahlgren Xunjia Cheng Yaming Cao Qijun Chen
author_sort	Zhiguang Chang
title	The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate
title_short	The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate
title_full	The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate
title_fullStr	The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate
title_full_unstemmed	The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate
title_sort	tatd-like dnase of plasmodium is a virulence factor and a potential malaria vaccine candidate
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/c7e8d6a556d440b9b0c2ceedd465c7f4
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The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate

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