The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate
Neutrophil extracellular traps (NETs), composed of DNA and proteases, contribute to the innate immune response by capturing pathogens. Here, Chang et al. identify a NET-degrading DNase in Plasmodiumparasites and show that immunization with this protein provides protective immunity in a malaria mouse...
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Auteurs principaux: | Zhiguang Chang, Ning Jiang, Yuanyuan Zhang, Huijun Lu, Jigang Yin, Mats Wahlgren, Xunjia Cheng, Yaming Cao, Qijun Chen |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
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Accès en ligne: | https://doaj.org/article/c7e8d6a556d440b9b0c2ceedd465c7f4 |
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