The TatD-like DNase of Plasmodium is a virulence factor and a potential malaria vaccine candidate

Neutrophil extracellular traps (NETs), composed of DNA and proteases, contribute to the innate immune response by capturing pathogens. Here, Chang et al. identify a NET-degrading DNase in Plasmodiumparasites and show that immunization with this protein provides protective immunity in a malaria mouse...

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Bibliographic Details
Main Authors: Zhiguang Chang, Ning Jiang, Yuanyuan Zhang, Huijun Lu, Jigang Yin, Mats Wahlgren, Xunjia Cheng, Yaming Cao, Qijun Chen
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/c7e8d6a556d440b9b0c2ceedd465c7f4
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