Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption

Time-restricted feeding (TRF) has beneficial metabolic effects. Here the authors examine how TRF impacts muscle physiology using fly models of metabolically adverse conditions, including diet and genetic models of obesity as well as circadian rhythm disruption, and find that TRF ameliorates skeletal...

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Autores principales: Jesús E. Villanueva, Christopher Livelo, Adriana S. Trujillo, Sahaana Chandran, Brendon Woodworth, Leo Andrade, Hiep D. Le, Uri Manor, Satchidananda Panda, Girish C. Melkani
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/c7eb88caeb7f43849647d5eef7935207
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spelling oai:doaj.org-article:c7eb88caeb7f43849647d5eef79352072021-12-02T15:36:03ZTime-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption10.1038/s41467-019-10563-92041-1723https://doaj.org/article/c7eb88caeb7f43849647d5eef79352072019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10563-9https://doaj.org/toc/2041-1723Time-restricted feeding (TRF) has beneficial metabolic effects. Here the authors examine how TRF impacts muscle physiology using fly models of metabolically adverse conditions, including diet and genetic models of obesity as well as circadian rhythm disruption, and find that TRF ameliorates skeletal muscle dysfunction.Jesús E. VillanuevaChristopher LiveloAdriana S. TrujilloSahaana ChandranBrendon WoodworthLeo AndradeHiep D. LeUri ManorSatchidananda PandaGirish C. MelkaniNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jesús E. Villanueva
Christopher Livelo
Adriana S. Trujillo
Sahaana Chandran
Brendon Woodworth
Leo Andrade
Hiep D. Le
Uri Manor
Satchidananda Panda
Girish C. Melkani
Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption
description Time-restricted feeding (TRF) has beneficial metabolic effects. Here the authors examine how TRF impacts muscle physiology using fly models of metabolically adverse conditions, including diet and genetic models of obesity as well as circadian rhythm disruption, and find that TRF ameliorates skeletal muscle dysfunction.
format article
author Jesús E. Villanueva
Christopher Livelo
Adriana S. Trujillo
Sahaana Chandran
Brendon Woodworth
Leo Andrade
Hiep D. Le
Uri Manor
Satchidananda Panda
Girish C. Melkani
author_facet Jesús E. Villanueva
Christopher Livelo
Adriana S. Trujillo
Sahaana Chandran
Brendon Woodworth
Leo Andrade
Hiep D. Le
Uri Manor
Satchidananda Panda
Girish C. Melkani
author_sort Jesús E. Villanueva
title Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption
title_short Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption
title_full Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption
title_fullStr Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption
title_full_unstemmed Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption
title_sort time-restricted feeding restores muscle function in drosophila models of obesity and circadian-rhythm disruption
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/c7eb88caeb7f43849647d5eef7935207
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