Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption
Time-restricted feeding (TRF) has beneficial metabolic effects. Here the authors examine how TRF impacts muscle physiology using fly models of metabolically adverse conditions, including diet and genetic models of obesity as well as circadian rhythm disruption, and find that TRF ameliorates skeletal...
Saved in:
Main Authors: | , , , , , , , , , |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
|
Subjects: | |
Online Access: | https://doaj.org/article/c7eb88caeb7f43849647d5eef7935207 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:doaj.org-article:c7eb88caeb7f43849647d5eef7935207 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:c7eb88caeb7f43849647d5eef79352072021-12-02T15:36:03ZTime-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption10.1038/s41467-019-10563-92041-1723https://doaj.org/article/c7eb88caeb7f43849647d5eef79352072019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10563-9https://doaj.org/toc/2041-1723Time-restricted feeding (TRF) has beneficial metabolic effects. Here the authors examine how TRF impacts muscle physiology using fly models of metabolically adverse conditions, including diet and genetic models of obesity as well as circadian rhythm disruption, and find that TRF ameliorates skeletal muscle dysfunction.Jesús E. VillanuevaChristopher LiveloAdriana S. TrujilloSahaana ChandranBrendon WoodworthLeo AndradeHiep D. LeUri ManorSatchidananda PandaGirish C. MelkaniNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Jesús E. Villanueva Christopher Livelo Adriana S. Trujillo Sahaana Chandran Brendon Woodworth Leo Andrade Hiep D. Le Uri Manor Satchidananda Panda Girish C. Melkani Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption |
description |
Time-restricted feeding (TRF) has beneficial metabolic effects. Here the authors examine how TRF impacts muscle physiology using fly models of metabolically adverse conditions, including diet and genetic models of obesity as well as circadian rhythm disruption, and find that TRF ameliorates skeletal muscle dysfunction. |
format |
article |
author |
Jesús E. Villanueva Christopher Livelo Adriana S. Trujillo Sahaana Chandran Brendon Woodworth Leo Andrade Hiep D. Le Uri Manor Satchidananda Panda Girish C. Melkani |
author_facet |
Jesús E. Villanueva Christopher Livelo Adriana S. Trujillo Sahaana Chandran Brendon Woodworth Leo Andrade Hiep D. Le Uri Manor Satchidananda Panda Girish C. Melkani |
author_sort |
Jesús E. Villanueva |
title |
Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption |
title_short |
Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption |
title_full |
Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption |
title_fullStr |
Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption |
title_full_unstemmed |
Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption |
title_sort |
time-restricted feeding restores muscle function in drosophila models of obesity and circadian-rhythm disruption |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/c7eb88caeb7f43849647d5eef7935207 |
work_keys_str_mv |
AT jesusevillanueva timerestrictedfeedingrestoresmusclefunctionindrosophilamodelsofobesityandcircadianrhythmdisruption AT christopherlivelo timerestrictedfeedingrestoresmusclefunctionindrosophilamodelsofobesityandcircadianrhythmdisruption AT adrianastrujillo timerestrictedfeedingrestoresmusclefunctionindrosophilamodelsofobesityandcircadianrhythmdisruption AT sahaanachandran timerestrictedfeedingrestoresmusclefunctionindrosophilamodelsofobesityandcircadianrhythmdisruption AT brendonwoodworth timerestrictedfeedingrestoresmusclefunctionindrosophilamodelsofobesityandcircadianrhythmdisruption AT leoandrade timerestrictedfeedingrestoresmusclefunctionindrosophilamodelsofobesityandcircadianrhythmdisruption AT hiepdle timerestrictedfeedingrestoresmusclefunctionindrosophilamodelsofobesityandcircadianrhythmdisruption AT urimanor timerestrictedfeedingrestoresmusclefunctionindrosophilamodelsofobesityandcircadianrhythmdisruption AT satchidanandapanda timerestrictedfeedingrestoresmusclefunctionindrosophilamodelsofobesityandcircadianrhythmdisruption AT girishcmelkani timerestrictedfeedingrestoresmusclefunctionindrosophilamodelsofobesityandcircadianrhythmdisruption |
_version_ |
1718386380383453184 |