Molecular mechanism of light-driven sodium pumping

The Na+-pumping KR2 rhodopsin from Krokinobacter eikastus is a light-driven non-proton cation pump whose mechanism of pumping remains to be understood. Here authors solved crystal structures of the O-intermediate state of the pentameric form of KR2 and its D116N and H30A mutants, which sheds light o...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kirill Kovalev, Roman Astashkin, Ivan Gushchin, Philipp Orekhov, Dmytro Volkov, Egor Zinovev, Egor Marin, Maksim Rulev, Alexey Alekseev, Antoine Royant, Philippe Carpentier, Svetlana Vaganova, Dmitrii Zabelskii, Christian Baeken, Ilya Sergeev, Taras Balandin, Gleb Bourenkov, Xavier Carpena, Roeland Boer, Nina Maliar, Valentin Borshchevskiy, Georg Büldt, Ernst Bamberg, Valentin Gordeliy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c7ebae3993e6420a849c16a42789609d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c7ebae3993e6420a849c16a42789609d
record_format	dspace
spelling	oai:doaj.org-article:c7ebae3993e6420a849c16a42789609d2021-12-02T15:37:09ZMolecular mechanism of light-driven sodium pumping10.1038/s41467-020-16032-y2041-1723https://doaj.org/article/c7ebae3993e6420a849c16a42789609d2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16032-yhttps://doaj.org/toc/2041-1723The Na+-pumping KR2 rhodopsin from Krokinobacter eikastus is a light-driven non-proton cation pump whose mechanism of pumping remains to be understood. Here authors solved crystal structures of the O-intermediate state of the pentameric form of KR2 and its D116N and H30A mutants, which sheds light on the mechanism of non-proton cation light-driven pumping.Kirill KovalevRoman AstashkinIvan GushchinPhilipp OrekhovDmytro VolkovEgor ZinovevEgor MarinMaksim RulevAlexey AlekseevAntoine RoyantPhilippe CarpentierSvetlana VaganovaDmitrii ZabelskiiChristian BaekenIlya SergeevTaras BalandinGleb BourenkovXavier CarpenaRoeland BoerNina MaliarValentin BorshchevskiyGeorg BüldtErnst BambergValentin GordeliyNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kirill Kovalev Roman Astashkin Ivan Gushchin Philipp Orekhov Dmytro Volkov Egor Zinovev Egor Marin Maksim Rulev Alexey Alekseev Antoine Royant Philippe Carpentier Svetlana Vaganova Dmitrii Zabelskii Christian Baeken Ilya Sergeev Taras Balandin Gleb Bourenkov Xavier Carpena Roeland Boer Nina Maliar Valentin Borshchevskiy Georg Büldt Ernst Bamberg Valentin Gordeliy Molecular mechanism of light-driven sodium pumping
description	The Na+-pumping KR2 rhodopsin from Krokinobacter eikastus is a light-driven non-proton cation pump whose mechanism of pumping remains to be understood. Here authors solved crystal structures of the O-intermediate state of the pentameric form of KR2 and its D116N and H30A mutants, which sheds light on the mechanism of non-proton cation light-driven pumping.
format	article
author	Kirill Kovalev Roman Astashkin Ivan Gushchin Philipp Orekhov Dmytro Volkov Egor Zinovev Egor Marin Maksim Rulev Alexey Alekseev Antoine Royant Philippe Carpentier Svetlana Vaganova Dmitrii Zabelskii Christian Baeken Ilya Sergeev Taras Balandin Gleb Bourenkov Xavier Carpena Roeland Boer Nina Maliar Valentin Borshchevskiy Georg Büldt Ernst Bamberg Valentin Gordeliy
author_facet	Kirill Kovalev Roman Astashkin Ivan Gushchin Philipp Orekhov Dmytro Volkov Egor Zinovev Egor Marin Maksim Rulev Alexey Alekseev Antoine Royant Philippe Carpentier Svetlana Vaganova Dmitrii Zabelskii Christian Baeken Ilya Sergeev Taras Balandin Gleb Bourenkov Xavier Carpena Roeland Boer Nina Maliar Valentin Borshchevskiy Georg Büldt Ernst Bamberg Valentin Gordeliy
author_sort	Kirill Kovalev
title	Molecular mechanism of light-driven sodium pumping
title_short	Molecular mechanism of light-driven sodium pumping
title_full	Molecular mechanism of light-driven sodium pumping
title_fullStr	Molecular mechanism of light-driven sodium pumping
title_full_unstemmed	Molecular mechanism of light-driven sodium pumping
title_sort	molecular mechanism of light-driven sodium pumping
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c7ebae3993e6420a849c16a42789609d
work_keys_str_mv	AT kirillkovalev molecularmechanismoflightdrivensodiumpumping AT romanastashkin molecularmechanismoflightdrivensodiumpumping AT ivangushchin molecularmechanismoflightdrivensodiumpumping AT philipporekhov molecularmechanismoflightdrivensodiumpumping AT dmytrovolkov molecularmechanismoflightdrivensodiumpumping AT egorzinovev molecularmechanismoflightdrivensodiumpumping AT egormarin molecularmechanismoflightdrivensodiumpumping AT maksimrulev molecularmechanismoflightdrivensodiumpumping AT alexeyalekseev molecularmechanismoflightdrivensodiumpumping AT antoineroyant molecularmechanismoflightdrivensodiumpumping AT philippecarpentier molecularmechanismoflightdrivensodiumpumping AT svetlanavaganova molecularmechanismoflightdrivensodiumpumping AT dmitriizabelskii molecularmechanismoflightdrivensodiumpumping AT christianbaeken molecularmechanismoflightdrivensodiumpumping AT ilyasergeev molecularmechanismoflightdrivensodiumpumping AT tarasbalandin molecularmechanismoflightdrivensodiumpumping AT glebbourenkov molecularmechanismoflightdrivensodiumpumping AT xaviercarpena molecularmechanismoflightdrivensodiumpumping AT roelandboer molecularmechanismoflightdrivensodiumpumping AT ninamaliar molecularmechanismoflightdrivensodiumpumping AT valentinborshchevskiy molecularmechanismoflightdrivensodiumpumping AT georgbuldt molecularmechanismoflightdrivensodiumpumping AT ernstbamberg molecularmechanismoflightdrivensodiumpumping AT valentingordeliy molecularmechanismoflightdrivensodiumpumping
_version_	1718386257922359296

Molecular mechanism of light-driven sodium pumping

Ejemplares similares