Guanylate Binding Proteins Restrict <named-content content-type="genus-species">Leishmania donovani</named-content> Growth in Nonphagocytic Cells Independent of Parasitophorous Vacuolar Targeting

Guanylate Binding Proteins Restrict <named-content content-type="genus-species">Leishmania donovani</named-content> Growth in Nonphagocytic Cells Independent of Parasitophorous Vacuolar Targeting

ABSTRACT Interferon (IFN)-inducible guanylate binding proteins (GBPs) play important roles in host defense against many intracellular pathogens that reside within pathogen-containing vacuoles (PVs). For instance, members of the GBP family translocate to PVs occupied by the protozoan pathogen Toxopla...

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Autores principales: Arun Kumar Haldar, Utsav Nigam, Masahiro Yamamoto, Jörn Coers, Neena Goyal
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
Leishmania
nonphagocytic cells
guanylate binding proteins
GBP
GTPases
IRGM
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/c7f263c1d4714a65b0e4676566ce3749
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