Vitamin D ameliorates adipose browning in chronic kidney disease cachexia

Vitamin D ameliorates adipose browning in chronic kidney disease cachexia

Abstract Patients with chronic kidney disease (CKD) are often 25(OH)D3 and 1,25(OH)2D3 insufficient. We studied whether vitamin D repletion could correct aberrant adipose tissue and muscle metabolism in a mouse model of CKD-associated cachexia. Intraperitoneal administration of 25(OH)D3 and 1,25(OH)...

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Main Authors: Wai W. Cheung, Wei Ding, Hal M. Hoffman, Zhen Wang, Sheng Hao, Ronghao Zheng, Alex Gonzalez, Jian-Ying Zhan, Ping Zhou, Shiping Li, Mary C. Esparza, Richard L. Lieber, Robert H. Mak
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/c7f89d5c634042d6a54496a2da92b2bc
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https://doaj.org/article/c7f89d5c634042d6a54496a2da92b2bc

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