Defining skin aging and its risk factors: a systematic review and meta-analysis

Abstract Skin aging has been defined to encompass both intrinsic and extrinsic aging, with extrinsic aging effected by environmental influences and overlaying the effects of chronological aging. The risk factors of skin aging have been studied previously, using methods of quantifying skin aging. How...

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Autores principales:	Qi Yi Ambrose Wong, Fook Tim Chew
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c7fa46d59a9d4506b399e1efbb9716e5
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spelling	oai:doaj.org-article:c7fa46d59a9d4506b399e1efbb9716e52021-11-14T12:19:20ZDefining skin aging and its risk factors: a systematic review and meta-analysis10.1038/s41598-021-01573-z2045-2322https://doaj.org/article/c7fa46d59a9d4506b399e1efbb9716e52021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01573-zhttps://doaj.org/toc/2045-2322Abstract Skin aging has been defined to encompass both intrinsic and extrinsic aging, with extrinsic aging effected by environmental influences and overlaying the effects of chronological aging. The risk factors of skin aging have been studied previously, using methods of quantifying skin aging. However, these studies have yet to be reviewed. To better understand skin aging risk factors and collate the available data, we aimed to conduct a systematic review and meta-analysis. We conducted our systematic review in compliance with Preferred Reporting Item for Systematic Review and Meta-Analyses (PRISMA) guidelines. Embase, PubMed and Web of Science databases were searched in October 2020 using specific search strategies. Where odds ratios were reported, meta-analyses were conducted using the random effects model. Otherwise, significant factors were reported in this review. We identified seven notable risk factors for various skin aging phenotypes: age, gender, ethnicity, air pollution, nutrition, smoking, sun exposure. This review’s results will guide future works, such as those aiming to examine the interaction between genetic and environmental influences.Qi Yi Ambrose WongFook Tim ChewNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Qi Yi Ambrose Wong Fook Tim Chew Defining skin aging and its risk factors: a systematic review and meta-analysis
description	Abstract Skin aging has been defined to encompass both intrinsic and extrinsic aging, with extrinsic aging effected by environmental influences and overlaying the effects of chronological aging. The risk factors of skin aging have been studied previously, using methods of quantifying skin aging. However, these studies have yet to be reviewed. To better understand skin aging risk factors and collate the available data, we aimed to conduct a systematic review and meta-analysis. We conducted our systematic review in compliance with Preferred Reporting Item for Systematic Review and Meta-Analyses (PRISMA) guidelines. Embase, PubMed and Web of Science databases were searched in October 2020 using specific search strategies. Where odds ratios were reported, meta-analyses were conducted using the random effects model. Otherwise, significant factors were reported in this review. We identified seven notable risk factors for various skin aging phenotypes: age, gender, ethnicity, air pollution, nutrition, smoking, sun exposure. This review’s results will guide future works, such as those aiming to examine the interaction between genetic and environmental influences.
format	article
author	Qi Yi Ambrose Wong Fook Tim Chew
author_facet	Qi Yi Ambrose Wong Fook Tim Chew
author_sort	Qi Yi Ambrose Wong
title	Defining skin aging and its risk factors: a systematic review and meta-analysis
title_short	Defining skin aging and its risk factors: a systematic review and meta-analysis
title_full	Defining skin aging and its risk factors: a systematic review and meta-analysis
title_fullStr	Defining skin aging and its risk factors: a systematic review and meta-analysis
title_full_unstemmed	Defining skin aging and its risk factors: a systematic review and meta-analysis
title_sort	defining skin aging and its risk factors: a systematic review and meta-analysis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c7fa46d59a9d4506b399e1efbb9716e5
work_keys_str_mv	AT qiyiambrosewong definingskinaginganditsriskfactorsasystematicreviewandmetaanalysis AT fooktimchew definingskinaginganditsriskfactorsasystematicreviewandmetaanalysis
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Defining skin aging and its risk factors: a systematic review and meta-analysis

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