Defining skin aging and its risk factors: a systematic review and meta-analysis
Abstract Skin aging has been defined to encompass both intrinsic and extrinsic aging, with extrinsic aging effected by environmental influences and overlaying the effects of chronological aging. The risk factors of skin aging have been studied previously, using methods of quantifying skin aging. How...
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2021
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oai:doaj.org-article:c7fa46d59a9d4506b399e1efbb9716e52021-11-14T12:19:20ZDefining skin aging and its risk factors: a systematic review and meta-analysis10.1038/s41598-021-01573-z2045-2322https://doaj.org/article/c7fa46d59a9d4506b399e1efbb9716e52021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01573-zhttps://doaj.org/toc/2045-2322Abstract Skin aging has been defined to encompass both intrinsic and extrinsic aging, with extrinsic aging effected by environmental influences and overlaying the effects of chronological aging. The risk factors of skin aging have been studied previously, using methods of quantifying skin aging. However, these studies have yet to be reviewed. To better understand skin aging risk factors and collate the available data, we aimed to conduct a systematic review and meta-analysis. We conducted our systematic review in compliance with Preferred Reporting Item for Systematic Review and Meta-Analyses (PRISMA) guidelines. Embase, PubMed and Web of Science databases were searched in October 2020 using specific search strategies. Where odds ratios were reported, meta-analyses were conducted using the random effects model. Otherwise, significant factors were reported in this review. We identified seven notable risk factors for various skin aging phenotypes: age, gender, ethnicity, air pollution, nutrition, smoking, sun exposure. This review’s results will guide future works, such as those aiming to examine the interaction between genetic and environmental influences.Qi Yi Ambrose WongFook Tim ChewNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021) |
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Medicine R Science Q Qi Yi Ambrose Wong Fook Tim Chew Defining skin aging and its risk factors: a systematic review and meta-analysis |
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Abstract Skin aging has been defined to encompass both intrinsic and extrinsic aging, with extrinsic aging effected by environmental influences and overlaying the effects of chronological aging. The risk factors of skin aging have been studied previously, using methods of quantifying skin aging. However, these studies have yet to be reviewed. To better understand skin aging risk factors and collate the available data, we aimed to conduct a systematic review and meta-analysis. We conducted our systematic review in compliance with Preferred Reporting Item for Systematic Review and Meta-Analyses (PRISMA) guidelines. Embase, PubMed and Web of Science databases were searched in October 2020 using specific search strategies. Where odds ratios were reported, meta-analyses were conducted using the random effects model. Otherwise, significant factors were reported in this review. We identified seven notable risk factors for various skin aging phenotypes: age, gender, ethnicity, air pollution, nutrition, smoking, sun exposure. This review’s results will guide future works, such as those aiming to examine the interaction between genetic and environmental influences. |
format |
article |
author |
Qi Yi Ambrose Wong Fook Tim Chew |
author_facet |
Qi Yi Ambrose Wong Fook Tim Chew |
author_sort |
Qi Yi Ambrose Wong |
title |
Defining skin aging and its risk factors: a systematic review and meta-analysis |
title_short |
Defining skin aging and its risk factors: a systematic review and meta-analysis |
title_full |
Defining skin aging and its risk factors: a systematic review and meta-analysis |
title_fullStr |
Defining skin aging and its risk factors: a systematic review and meta-analysis |
title_full_unstemmed |
Defining skin aging and its risk factors: a systematic review and meta-analysis |
title_sort |
defining skin aging and its risk factors: a systematic review and meta-analysis |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/c7fa46d59a9d4506b399e1efbb9716e5 |
work_keys_str_mv |
AT qiyiambrosewong definingskinaginganditsriskfactorsasystematicreviewandmetaanalysis AT fooktimchew definingskinaginganditsriskfactorsasystematicreviewandmetaanalysis |
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1718429314565799936 |