Analysis of cardiomyocyte clonal expansion during mouse heart development and injury

During cardiac tissue formation it is unclear whether newly generated myocytes originate from cardiac progenitor cells or from pre-existing cardiomyocytes. Here, the authors use a stochastic four-colour reporter system (Rainbow) to identify the source of new cardiomyocytes during mouse development.

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Autores principales:	Konstantina-Ioanna Sereti, Ngoc B. Nguyen, Paniz Kamran, Peng Zhao, Sara Ranjbarvaziri, Shuin Park, Shan Sabri, James L. Engel, Kevin Sung, Rajan P. Kulkarni, Yichen Ding, Tzung K. Hsiai, Kathrin Plath, Jason Ernst, Debashis Sahoo, Hanna K.A. Mikkola, M. Luisa Iruela-Arispe, Reza Ardehali
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c802b51efbb94834a80f05d3baafd799
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spelling	oai:doaj.org-article:c802b51efbb94834a80f05d3baafd7992021-12-02T17:31:14ZAnalysis of cardiomyocyte clonal expansion during mouse heart development and injury10.1038/s41467-018-02891-z2041-1723https://doaj.org/article/c802b51efbb94834a80f05d3baafd7992018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02891-zhttps://doaj.org/toc/2041-1723During cardiac tissue formation it is unclear whether newly generated myocytes originate from cardiac progenitor cells or from pre-existing cardiomyocytes. Here, the authors use a stochastic four-colour reporter system (Rainbow) to identify the source of new cardiomyocytes during mouse development.Konstantina-Ioanna SeretiNgoc B. NguyenPaniz KamranPeng ZhaoSara RanjbarvaziriShuin ParkShan SabriJames L. EngelKevin SungRajan P. KulkarniYichen DingTzung K. HsiaiKathrin PlathJason ErnstDebashis SahooHanna K.A. MikkolaM. Luisa Iruela-ArispeReza ArdehaliNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Konstantina-Ioanna Sereti Ngoc B. Nguyen Paniz Kamran Peng Zhao Sara Ranjbarvaziri Shuin Park Shan Sabri James L. Engel Kevin Sung Rajan P. Kulkarni Yichen Ding Tzung K. Hsiai Kathrin Plath Jason Ernst Debashis Sahoo Hanna K.A. Mikkola M. Luisa Iruela-Arispe Reza Ardehali Analysis of cardiomyocyte clonal expansion during mouse heart development and injury
description	During cardiac tissue formation it is unclear whether newly generated myocytes originate from cardiac progenitor cells or from pre-existing cardiomyocytes. Here, the authors use a stochastic four-colour reporter system (Rainbow) to identify the source of new cardiomyocytes during mouse development.
format	article
author	Konstantina-Ioanna Sereti Ngoc B. Nguyen Paniz Kamran Peng Zhao Sara Ranjbarvaziri Shuin Park Shan Sabri James L. Engel Kevin Sung Rajan P. Kulkarni Yichen Ding Tzung K. Hsiai Kathrin Plath Jason Ernst Debashis Sahoo Hanna K.A. Mikkola M. Luisa Iruela-Arispe Reza Ardehali
author_facet	Konstantina-Ioanna Sereti Ngoc B. Nguyen Paniz Kamran Peng Zhao Sara Ranjbarvaziri Shuin Park Shan Sabri James L. Engel Kevin Sung Rajan P. Kulkarni Yichen Ding Tzung K. Hsiai Kathrin Plath Jason Ernst Debashis Sahoo Hanna K.A. Mikkola M. Luisa Iruela-Arispe Reza Ardehali
author_sort	Konstantina-Ioanna Sereti
title	Analysis of cardiomyocyte clonal expansion during mouse heart development and injury
title_short	Analysis of cardiomyocyte clonal expansion during mouse heart development and injury
title_full	Analysis of cardiomyocyte clonal expansion during mouse heart development and injury
title_fullStr	Analysis of cardiomyocyte clonal expansion during mouse heart development and injury
title_full_unstemmed	Analysis of cardiomyocyte clonal expansion during mouse heart development and injury
title_sort	analysis of cardiomyocyte clonal expansion during mouse heart development and injury
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c802b51efbb94834a80f05d3baafd799
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Analysis of cardiomyocyte clonal expansion during mouse heart development and injury

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