Identification of MicroRNA–mRNA Networks in Melanoma and Their Association with PD-1 Checkpoint Blockade Outcomes

Identification of MicroRNA–mRNA Networks in Melanoma and Their Association with PD-1 Checkpoint Blockade Outcomes

Metastatic melanoma is a deadly malignancy with poor outcomes historically. Immuno-oncology (IO) agents, targeting immune checkpoint molecules such as cytotoxic T-lymphocyte associated protein-4 (CTLA-4) and programmed cell death-1 (PD-1), have revolutionized melanoma treatment and outcomes, achievi...

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Autores principales: Robert A. Szczepaniak Sloane, Michael G. White, Russell G. Witt, Anik Banerjee, Michael A. Davies, Guangchun Han, Elizabeth Burton, Nadim Ajami, Julie M. Simon, Chantale Bernatchez, Lauren E. Haydu, Hussein A. Tawbi, Jeffrey E. Gershenwald, Emily Keung, Merrick Ross, Jennifer McQuade, Rodabe N. Amaria, Khalida Wani, Alexander J. Lazar, Scott E. Woodman, Linghua Wang, Miles C. Andrews, Jennifer A. Wargo
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
microRNA
melanoma
immune checkpoint blockade
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/c8064d6d4da44883816ebcc8ea0a1965
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