Progress in stem cell-derived technologies for hepatocellular carcinoma

Rajagopal N AravalliDepartment of Radiology, University of Minnesota Medical School, Minneapolis, MN, USAAbstract: Primary hepatocellular carcinoma (HCC) is a common malignancy that has a poor prognosis because it is often diagnosed at an advanced stage. HCC normally develops as a consequence of und...

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Autor principal:	Rajagopal N Aravalli
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Cytology QH573-671
Acceso en línea:	https://doaj.org/article/c8073b7f772b4d6c8233527cd2bf8bed
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spelling	oai:doaj.org-article:c8073b7f772b4d6c8233527cd2bf8bed2021-12-02T01:40:09ZProgress in stem cell-derived technologies for hepatocellular carcinoma1178-6957https://doaj.org/article/c8073b7f772b4d6c8233527cd2bf8bed2010-05-01T00:00:00Zhttp://www.dovepress.com/progress-in-stem-cell-derived-technologies-for-hepatocellular-carcinom-a4354https://doaj.org/toc/1178-6957Rajagopal N AravalliDepartment of Radiology, University of Minnesota Medical School, Minneapolis, MN, USAAbstract: Primary hepatocellular carcinoma (HCC) is a common malignancy that has a poor prognosis because it is often diagnosed at an advanced stage. HCC normally develops as a consequence of underlying liver disease and is most often associated with cirrhosis. Surgical resection and liver transplantation are the current best options to treat liver cancer. However, problems associated with liver transplantation, such as shortage of donors, risk of immune rejection, and tissue damage following surgery provided the impetus for development of alternative therapies. The emerging field of stem cell therapy has raised hopes for finding curative options for liver cancer. Stem cells have the ability not only to proliferate after transplantation but also to differentiate into most mammalian cell types in vivo. In this review, progress on stem cell-derived technologies for the treatment of liver cancer is discussed.Keywords: liver, cancer, stem cell, therapy, hepatocellular carcinoma Rajagopal N AravalliDove Medical PressarticleCytologyQH573-671ENStem Cells and Cloning: Advances and Applications, Vol 2010, Iss default, Pp 81-92 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Cytology QH573-671
spellingShingle	Cytology QH573-671 Rajagopal N Aravalli Progress in stem cell-derived technologies for hepatocellular carcinoma
description	Rajagopal N AravalliDepartment of Radiology, University of Minnesota Medical School, Minneapolis, MN, USAAbstract: Primary hepatocellular carcinoma (HCC) is a common malignancy that has a poor prognosis because it is often diagnosed at an advanced stage. HCC normally develops as a consequence of underlying liver disease and is most often associated with cirrhosis. Surgical resection and liver transplantation are the current best options to treat liver cancer. However, problems associated with liver transplantation, such as shortage of donors, risk of immune rejection, and tissue damage following surgery provided the impetus for development of alternative therapies. The emerging field of stem cell therapy has raised hopes for finding curative options for liver cancer. Stem cells have the ability not only to proliferate after transplantation but also to differentiate into most mammalian cell types in vivo. In this review, progress on stem cell-derived technologies for the treatment of liver cancer is discussed.Keywords: liver, cancer, stem cell, therapy, hepatocellular carcinoma
format	article
author	Rajagopal N Aravalli
author_facet	Rajagopal N Aravalli
author_sort	Rajagopal N Aravalli
title	Progress in stem cell-derived technologies for hepatocellular carcinoma
title_short	Progress in stem cell-derived technologies for hepatocellular carcinoma
title_full	Progress in stem cell-derived technologies for hepatocellular carcinoma
title_fullStr	Progress in stem cell-derived technologies for hepatocellular carcinoma
title_full_unstemmed	Progress in stem cell-derived technologies for hepatocellular carcinoma
title_sort	progress in stem cell-derived technologies for hepatocellular carcinoma
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/c8073b7f772b4d6c8233527cd2bf8bed
work_keys_str_mv	AT rajagopalnaravalli progressinstemcellderivedtechnologiesforhepatocellularcarcinoma
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Progress in stem cell-derived technologies for hepatocellular carcinoma

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