Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.

<h4>Aims</h4>To describe trends in the incidence of non-traumatic amputations among people with and without diabetes and estimate the relative risk of an individual with diabetes undergoing a lower extremity amputation compared to an individual without diabetes in the Republic of Ireland...

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Autores principales:	Claire M Buckley, Anne O'Farrell, Ronan J Canavan, Anthony D Lynch, Davida V De La Harpe, Colin P Bradley, Ivan J Perry
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c8132b13678043d888c434f0932b9668
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spelling	oai:doaj.org-article:c8132b13678043d888c434f0932b96682021-11-18T07:10:18ZTrends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.1932-620310.1371/journal.pone.0041492https://doaj.org/article/c8132b13678043d888c434f0932b96682012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22859991/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Aims</h4>To describe trends in the incidence of non-traumatic amputations among people with and without diabetes and estimate the relative risk of an individual with diabetes undergoing a lower extremity amputation compared to an individual without diabetes in the Republic of Ireland.<h4>Methods</h4>All adults who underwent a nontraumatic amputation during 2005 to 2009 were identified using HIPE (Hospital In-patient Enquiry) data. Participants were classified as having diabetes or not having diabetes. Incidence rates were calculated using the number of discharges for diabetes and non-diabetes related lower extremity amputations as the numerator and estimates of the resident population with and without diabetes as the denominator. Age-adjusted incidence rates were used for trend analysis.<h4>Results</h4>Total diabetes-related amputation rates increased non-significantly during the study period; 144.2 in 2005 to 175.7 in 2009 per 100,000 people with diabetes (p = 0.11). Total non-diabetes related amputation rates dropped non-significantly from 12.0 in 2005 to 9.2 in 2009 per 100,000 people without diabetes (p = 0.16). An individual with diabetes was 22.3 (95% CI 19.1-26.1) times more likely to undergo a nontraumatic amputation than an individual without diabetes in 2005 and this did not change significantly by 2009.<h4>Discussion</h4>This study provides the first national estimate of lower extremity amputation rates in the Republic of Ireland. Diabetes-related amputation rates have remained steady despite an increase in people with diabetes. These estimates provide a base-line and will allow follow-up over time.Claire M BuckleyAnne O'FarrellRonan J CanavanAnthony D LynchDavida V De La HarpeColin P BradleyIvan J PerryPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 7, p e41492 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Claire M Buckley Anne O'Farrell Ronan J Canavan Anthony D Lynch Davida V De La Harpe Colin P Bradley Ivan J Perry Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.
description	<h4>Aims</h4>To describe trends in the incidence of non-traumatic amputations among people with and without diabetes and estimate the relative risk of an individual with diabetes undergoing a lower extremity amputation compared to an individual without diabetes in the Republic of Ireland.<h4>Methods</h4>All adults who underwent a nontraumatic amputation during 2005 to 2009 were identified using HIPE (Hospital In-patient Enquiry) data. Participants were classified as having diabetes or not having diabetes. Incidence rates were calculated using the number of discharges for diabetes and non-diabetes related lower extremity amputations as the numerator and estimates of the resident population with and without diabetes as the denominator. Age-adjusted incidence rates were used for trend analysis.<h4>Results</h4>Total diabetes-related amputation rates increased non-significantly during the study period; 144.2 in 2005 to 175.7 in 2009 per 100,000 people with diabetes (p = 0.11). Total non-diabetes related amputation rates dropped non-significantly from 12.0 in 2005 to 9.2 in 2009 per 100,000 people without diabetes (p = 0.16). An individual with diabetes was 22.3 (95% CI 19.1-26.1) times more likely to undergo a nontraumatic amputation than an individual without diabetes in 2005 and this did not change significantly by 2009.<h4>Discussion</h4>This study provides the first national estimate of lower extremity amputation rates in the Republic of Ireland. Diabetes-related amputation rates have remained steady despite an increase in people with diabetes. These estimates provide a base-line and will allow follow-up over time.
format	article
author	Claire M Buckley Anne O'Farrell Ronan J Canavan Anthony D Lynch Davida V De La Harpe Colin P Bradley Ivan J Perry
author_facet	Claire M Buckley Anne O'Farrell Ronan J Canavan Anthony D Lynch Davida V De La Harpe Colin P Bradley Ivan J Perry
author_sort	Claire M Buckley
title	Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.
title_short	Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.
title_full	Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.
title_fullStr	Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.
title_full_unstemmed	Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.
title_sort	trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the republic of ireland.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/c8132b13678043d888c434f0932b9668
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Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.

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