$Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy$
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Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy

Hypoxia in solid tumors is an important factor in radiation therapy resistance, but partial pressures of oxygen in the tissue are heterogenous and difficult to measure. Here the authors develop Cherenkov excited phosphorescence imaging using oxygen probe Oxyphor PtG4 to spatially track oxygen distri...

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Autores principales:	Xu Cao, Srinivasa Rao Allu, Shudong Jiang, Mengyu Jia, Jason R. Gunn, Cuiping Yao, Ethan P. LaRochelle, Jennifer R. Shell, Petr Bruza, David J. Gladstone, Lesley A. Jarvis, Jie Tian, Sergei A. Vinogradov, Brian W. Pogue
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c818b60b72b54223bcc9d9c1c23bb345
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spelling	oai:doaj.org-article:c818b60b72b54223bcc9d9c1c23bb3452021-12-02T16:56:33ZTissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy10.1038/s41467-020-14415-92041-1723https://doaj.org/article/c818b60b72b54223bcc9d9c1c23bb3452020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14415-9https://doaj.org/toc/2041-1723Hypoxia in solid tumors is an important factor in radiation therapy resistance, but partial pressures of oxygen in the tissue are heterogenous and difficult to measure. Here the authors develop Cherenkov excited phosphorescence imaging using oxygen probe Oxyphor PtG4 to spatially track oxygen distributions in tumors during fractionated radiotherapy.Xu CaoSrinivasa Rao AlluShudong JiangMengyu JiaJason R. GunnCuiping YaoEthan P. LaRochelleJennifer R. ShellPetr BruzaDavid J. GladstoneLesley A. JarvisJie TianSergei A. VinogradovBrian W. PogueNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xu Cao Srinivasa Rao Allu Shudong Jiang Mengyu Jia Jason R. Gunn Cuiping Yao Ethan P. LaRochelle Jennifer R. Shell Petr Bruza David J. Gladstone Lesley A. Jarvis Jie Tian Sergei A. Vinogradov Brian W. Pogue Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy
description	Hypoxia in solid tumors is an important factor in radiation therapy resistance, but partial pressures of oxygen in the tissue are heterogenous and difficult to measure. Here the authors develop Cherenkov excited phosphorescence imaging using oxygen probe Oxyphor PtG4 to spatially track oxygen distributions in tumors during fractionated radiotherapy.
format	article
author	Xu Cao Srinivasa Rao Allu Shudong Jiang Mengyu Jia Jason R. Gunn Cuiping Yao Ethan P. LaRochelle Jennifer R. Shell Petr Bruza David J. Gladstone Lesley A. Jarvis Jie Tian Sergei A. Vinogradov Brian W. Pogue
author_facet	Xu Cao Srinivasa Rao Allu Shudong Jiang Mengyu Jia Jason R. Gunn Cuiping Yao Ethan P. LaRochelle Jennifer R. Shell Petr Bruza David J. Gladstone Lesley A. Jarvis Jie Tian Sergei A. Vinogradov Brian W. Pogue
author_sort	Xu Cao
title	Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy
title_short	Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy
title_full	Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy
title_fullStr	Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy
title_full_unstemmed	Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy
title_sort	tissue po2 distributions in xenograft tumors dynamically imaged by cherenkov-excited phosphorescence during fractionated radiation therapy
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c818b60b72b54223bcc9d9c1c23bb345
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Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy

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