Modulation of auditory sensory memory by chronic clinical pain and acute experimental pain: a mismatch negativity study

Abstract Pain, especially chronic pain, can lead to cognitive deficits. Mismatch negativity (MMN) is a change-specific component of the auditory event-related brain potential (ERP) that is thought to provide a unique window into sensory memory processes. The present study was designed to determine h...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lu Fan, Ya-Bin Sun, Ze-Kun Sun, Ning Wang, Fei Luo, Feng Yu, Jin-Yan Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Auditory Sensory Memory Mismatch Negativity (MMN) Chronic Pain Patients Event-related Brain Potentials (ERPs) Long ISI Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c828ce0b7ab640589f1fdc65bf1e0b3d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c828ce0b7ab640589f1fdc65bf1e0b3d
record_format	dspace
spelling	oai:doaj.org-article:c828ce0b7ab640589f1fdc65bf1e0b3d2021-12-02T15:08:25ZModulation of auditory sensory memory by chronic clinical pain and acute experimental pain: a mismatch negativity study10.1038/s41598-018-34099-y2045-2322https://doaj.org/article/c828ce0b7ab640589f1fdc65bf1e0b3d2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-34099-yhttps://doaj.org/toc/2045-2322Abstract Pain, especially chronic pain, can lead to cognitive deficits. Mismatch negativity (MMN) is a change-specific component of the auditory event-related brain potential (ERP) that is thought to provide a unique window into sensory memory processes. The present study was designed to determine how chronic and acute pain affects auditory sensory memory. In experiment 1, MMNs elicited by standard and deviant auditory stimuli at short and long inter-stimulus intervals (ISIs) were compared between trigeminal neuralgia (TN) patients and demographically matched healthy controls (HCs). The TN patients were found to have stronger attenuation of the MMN at longer ISIs than HCs. Correlation analysis revealed a significant positive correlation between the sensory subscale of McGill Pain Questionnaire and MMN amplitude reduction across ISI conditions. In experiment 2, MMNs recorded before, during, and after the cold pressor test were compared in healthy subjects. MMN amplitude was significantly reduced during pain exposure and recovered immediately thereafter. These results suggest that both chronic pain and acute pain can interfere with automatic change detection processes in the brain. This study provides the first evidence that chronic pain patients have a faster auditory memory trace decay than HCs.Lu FanYa-Bin SunZe-Kun SunNing WangFei LuoFeng YuJin-Yan WangNature PortfolioarticleAuditory Sensory MemoryMismatch Negativity (MMN)Chronic Pain PatientsEvent-related Brain Potentials (ERPs)Long ISIMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Auditory Sensory Memory Mismatch Negativity (MMN) Chronic Pain Patients Event-related Brain Potentials (ERPs) Long ISI Medicine R Science Q
spellingShingle	Auditory Sensory Memory Mismatch Negativity (MMN) Chronic Pain Patients Event-related Brain Potentials (ERPs) Long ISI Medicine R Science Q Lu Fan Ya-Bin Sun Ze-Kun Sun Ning Wang Fei Luo Feng Yu Jin-Yan Wang Modulation of auditory sensory memory by chronic clinical pain and acute experimental pain: a mismatch negativity study
description	Abstract Pain, especially chronic pain, can lead to cognitive deficits. Mismatch negativity (MMN) is a change-specific component of the auditory event-related brain potential (ERP) that is thought to provide a unique window into sensory memory processes. The present study was designed to determine how chronic and acute pain affects auditory sensory memory. In experiment 1, MMNs elicited by standard and deviant auditory stimuli at short and long inter-stimulus intervals (ISIs) were compared between trigeminal neuralgia (TN) patients and demographically matched healthy controls (HCs). The TN patients were found to have stronger attenuation of the MMN at longer ISIs than HCs. Correlation analysis revealed a significant positive correlation between the sensory subscale of McGill Pain Questionnaire and MMN amplitude reduction across ISI conditions. In experiment 2, MMNs recorded before, during, and after the cold pressor test were compared in healthy subjects. MMN amplitude was significantly reduced during pain exposure and recovered immediately thereafter. These results suggest that both chronic pain and acute pain can interfere with automatic change detection processes in the brain. This study provides the first evidence that chronic pain patients have a faster auditory memory trace decay than HCs.
format	article
author	Lu Fan Ya-Bin Sun Ze-Kun Sun Ning Wang Fei Luo Feng Yu Jin-Yan Wang
author_facet	Lu Fan Ya-Bin Sun Ze-Kun Sun Ning Wang Fei Luo Feng Yu Jin-Yan Wang
author_sort	Lu Fan
title	Modulation of auditory sensory memory by chronic clinical pain and acute experimental pain: a mismatch negativity study
title_short	Modulation of auditory sensory memory by chronic clinical pain and acute experimental pain: a mismatch negativity study
title_full	Modulation of auditory sensory memory by chronic clinical pain and acute experimental pain: a mismatch negativity study
title_fullStr	Modulation of auditory sensory memory by chronic clinical pain and acute experimental pain: a mismatch negativity study
title_full_unstemmed	Modulation of auditory sensory memory by chronic clinical pain and acute experimental pain: a mismatch negativity study
title_sort	modulation of auditory sensory memory by chronic clinical pain and acute experimental pain: a mismatch negativity study
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c828ce0b7ab640589f1fdc65bf1e0b3d
work_keys_str_mv	AT lufan modulationofauditorysensorymemorybychronicclinicalpainandacuteexperimentalpainamismatchnegativitystudy AT yabinsun modulationofauditorysensorymemorybychronicclinicalpainandacuteexperimentalpainamismatchnegativitystudy AT zekunsun modulationofauditorysensorymemorybychronicclinicalpainandacuteexperimentalpainamismatchnegativitystudy AT ningwang modulationofauditorysensorymemorybychronicclinicalpainandacuteexperimentalpainamismatchnegativitystudy AT feiluo modulationofauditorysensorymemorybychronicclinicalpainandacuteexperimentalpainamismatchnegativitystudy AT fengyu modulationofauditorysensorymemorybychronicclinicalpainandacuteexperimentalpainamismatchnegativitystudy AT jinyanwang modulationofauditorysensorymemorybychronicclinicalpainandacuteexperimentalpainamismatchnegativitystudy
_version_	1718388148679999488

Modulation of auditory sensory memory by chronic clinical pain and acute experimental pain: a mismatch negativity study

Ejemplares similares