The role of insulin glulisine to improve glycemic control in children with diabetes mellitus

Anna Lih, Emily Hibbert, Tang Wong, Christian M Girgis, Nidhi Garg, John N CarterDepartment of Endocrinology and Metabolism, Concord Hospital, NSW, Australia; University of Sydney, Camperdown, NSW, AustraliaAbstract: Glulisine (Apidra®) is a rapid-acting human insulin analog approved for use...

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Autores principales:	Carter J, Lih A, Hibbert EL, Wong T, Girgis C, Garg
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Glulisine pediatrics Type 1 diabetes mellitus Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/c82bb31794a241119c4bc78ea685d3ef
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spelling	oai:doaj.org-article:c82bb31794a241119c4bc78ea685d3ef2021-12-02T02:24:32ZThe role of insulin glulisine to improve glycemic control in children with diabetes mellitus1178-7007https://doaj.org/article/c82bb31794a241119c4bc78ea685d3ef2010-11-01T00:00:00Zhttps://www.dovepress.com/the-role-of-insulin-glulisine-to-improve-glycemic-control-in-children--peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Anna Lih, Emily Hibbert, Tang Wong, Christian M Girgis, Nidhi Garg, John N CarterDepartment of Endocrinology and Metabolism, Concord Hospital, NSW, Australia; University of Sydney, Camperdown, NSW, AustraliaAbstract: Glulisine (Apidra®) is a rapid-acting human insulin analog approved for use in children with diabetes mellitus ≥4 years of age. Management of children with type 1 diabetes has seen a shift in favor of mimicking normal physiological insulin responses with multiple daily injections or continuous subcutaneous insulin infusions (CSII). Few studies have compared the rapid-acting insulin analogs in this population but limited data indicate that glulisine is as effective as lispro when used in a basal–bolus regimen. This review appraises the current available studies and reviews on insulin glulisine in children. An extensive keyword search of ‘insulin glulisine’, ‘insulin analogs’, and ‘Apidra’ in the pediatric population was performed. These studies have suggested that glulisine is safe, well tolerated, and is an effective option in the diabetes armamentarium. Further studies are needed to determine its safety for use in CSII pumps in the pediatric population.Keywords: glulisine, pediatrics, type 1 diabetes mellitusCarter JLih AHibbert ELWong TGirgis CGargDove Medical PressarticleGlulisinepediatricsType 1 diabetes mellitusSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 3, Pp 403-412 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Glulisine pediatrics Type 1 diabetes mellitus Specialties of internal medicine RC581-951
spellingShingle	Glulisine pediatrics Type 1 diabetes mellitus Specialties of internal medicine RC581-951 Carter J Lih A Hibbert EL Wong T Girgis C Garg The role of insulin glulisine to improve glycemic control in children with diabetes mellitus
description	Anna Lih, Emily Hibbert, Tang Wong, Christian M Girgis, Nidhi Garg, John N CarterDepartment of Endocrinology and Metabolism, Concord Hospital, NSW, Australia; University of Sydney, Camperdown, NSW, AustraliaAbstract: Glulisine (Apidra®) is a rapid-acting human insulin analog approved for use in children with diabetes mellitus ≥4 years of age. Management of children with type 1 diabetes has seen a shift in favor of mimicking normal physiological insulin responses with multiple daily injections or continuous subcutaneous insulin infusions (CSII). Few studies have compared the rapid-acting insulin analogs in this population but limited data indicate that glulisine is as effective as lispro when used in a basal–bolus regimen. This review appraises the current available studies and reviews on insulin glulisine in children. An extensive keyword search of ‘insulin glulisine’, ‘insulin analogs’, and ‘Apidra’ in the pediatric population was performed. These studies have suggested that glulisine is safe, well tolerated, and is an effective option in the diabetes armamentarium. Further studies are needed to determine its safety for use in CSII pumps in the pediatric population.Keywords: glulisine, pediatrics, type 1 diabetes mellitus
format	article
author	Carter J Lih A Hibbert EL Wong T Girgis C Garg
author_facet	Carter J Lih A Hibbert EL Wong T Girgis C Garg
author_sort	Carter J
title	The role of insulin glulisine to improve glycemic control in children with diabetes mellitus
title_short	The role of insulin glulisine to improve glycemic control in children with diabetes mellitus
title_full	The role of insulin glulisine to improve glycemic control in children with diabetes mellitus
title_fullStr	The role of insulin glulisine to improve glycemic control in children with diabetes mellitus
title_full_unstemmed	The role of insulin glulisine to improve glycemic control in children with diabetes mellitus
title_sort	role of insulin glulisine to improve glycemic control in children with diabetes mellitus
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/c82bb31794a241119c4bc78ea685d3ef
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The role of insulin glulisine to improve glycemic control in children with diabetes mellitus

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