An anionic human protein mediates cationic liposome delivery of genome editing proteins into mammalian cells

Inefficient delivery of proteins into mammalian cells limits their use in research and therapy. Here, the authors discover that ProTα, a small, intrinsically disordered human protein can facilitate efficient cationic lipid-mediated protein delivery of genome editing proteins into mammalian cells.

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Detalles Bibliográficos
Autores principales: Y. Bill Kim, Kevin T. Zhao, David B. Thompson, David R. Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Q
Acceso en línea:https://doaj.org/article/c835099de4814592bcbecee8ffae3aee
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