Prior fluid and electrolyte imbalance is associated with COVID-19 mortality

Plain language summary The clinical course of patients with COVID-19 is highly variable, with some patients barely affected and others dying. We wanted to better understand why this is the case and identify markers of COVID-19-associated mortality. To this end, we looked into the entire available me...

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Autores principales: Satu Nahkuri, Tim Becker, Vitalia Schueller, Steffen Massberg, Anna Bauer-Mehren
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c84131697e1b4219b64e04fd36f36dbc
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spelling oai:doaj.org-article:c84131697e1b4219b64e04fd36f36dbc2021-11-28T12:15:13ZPrior fluid and electrolyte imbalance is associated with COVID-19 mortality10.1038/s43856-021-00051-x2730-664Xhttps://doaj.org/article/c84131697e1b4219b64e04fd36f36dbc2021-11-01T00:00:00Zhttps://doi.org/10.1038/s43856-021-00051-xhttps://doaj.org/toc/2730-664XPlain language summary The clinical course of patients with COVID-19 is highly variable, with some patients barely affected and others dying. We wanted to better understand why this is the case and identify markers of COVID-19-associated mortality. To this end, we looked into the entire available medical history of more than 100,000 COVID-19 patients from the United States. We found that patients who had experienced a disturbance of electrolyte or fluid levels in the year before they contracted SARS-CoV-2 were more likely to die than patients without such a history. This observation suggests that careful monitoring and balancing of the hydration and electrolyte status during and even before a SARS-CoV-2 infection may be beneficial and possibly reduce the risk of death with COVID-19.Satu NahkuriTim BeckerVitalia SchuellerSteffen MassbergAnna Bauer-MehrenNature PortfolioarticleMedicineRENCommunications Medicine, Vol 1, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
spellingShingle Medicine
R
Satu Nahkuri
Tim Becker
Vitalia Schueller
Steffen Massberg
Anna Bauer-Mehren
Prior fluid and electrolyte imbalance is associated with COVID-19 mortality
description Plain language summary The clinical course of patients with COVID-19 is highly variable, with some patients barely affected and others dying. We wanted to better understand why this is the case and identify markers of COVID-19-associated mortality. To this end, we looked into the entire available medical history of more than 100,000 COVID-19 patients from the United States. We found that patients who had experienced a disturbance of electrolyte or fluid levels in the year before they contracted SARS-CoV-2 were more likely to die than patients without such a history. This observation suggests that careful monitoring and balancing of the hydration and electrolyte status during and even before a SARS-CoV-2 infection may be beneficial and possibly reduce the risk of death with COVID-19.
format article
author Satu Nahkuri
Tim Becker
Vitalia Schueller
Steffen Massberg
Anna Bauer-Mehren
author_facet Satu Nahkuri
Tim Becker
Vitalia Schueller
Steffen Massberg
Anna Bauer-Mehren
author_sort Satu Nahkuri
title Prior fluid and electrolyte imbalance is associated with COVID-19 mortality
title_short Prior fluid and electrolyte imbalance is associated with COVID-19 mortality
title_full Prior fluid and electrolyte imbalance is associated with COVID-19 mortality
title_fullStr Prior fluid and electrolyte imbalance is associated with COVID-19 mortality
title_full_unstemmed Prior fluid and electrolyte imbalance is associated with COVID-19 mortality
title_sort prior fluid and electrolyte imbalance is associated with covid-19 mortality
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c84131697e1b4219b64e04fd36f36dbc
work_keys_str_mv AT satunahkuri priorfluidandelectrolyteimbalanceisassociatedwithcovid19mortality
AT timbecker priorfluidandelectrolyteimbalanceisassociatedwithcovid19mortality
AT vitaliaschueller priorfluidandelectrolyteimbalanceisassociatedwithcovid19mortality
AT steffenmassberg priorfluidandelectrolyteimbalanceisassociatedwithcovid19mortality
AT annabauermehren priorfluidandelectrolyteimbalanceisassociatedwithcovid19mortality
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