Computational modeling of unphosphorylated CtrA:Cori binding in the Caulobacter cell cycle

Summary: In the alphaproteobacterium, Caulobacter crescentus, phosphorylated CtrA (CtrA∼P), a master regulatory protein, binds directly to the chromosome origin (Cori) to inhibit DNA replication. Using a mathematical model of CtrA binding at Cori site [d], we provide computational evidence that CtrA...

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Bibliographic Details
Main Authors: Bronson R. Weston, John J. Tyson, Yang Cao
Format: article
Language:EN
Published: Elsevier 2021
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Online Access:https://doaj.org/article/c84aecc762214e299ba19b6016248efd
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