QUANTIFICATION OF RETINAL NERVE FIBER LAYER FOR EARLY DETECTION OF ANTERIOR VISUAL PATHWAY LESIONS

Objective: To assess the role of quantification of retinal nerve fiber layer for early detection of anterior visual pathway lesions. Study Design: Case-control study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, from Jan to Jul 2019. Methodology: A total...

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Autores principales:	Noureen Malik, Hannan Masud, Muhammad Manzoor Awan
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	retinal nerve fiber layer anterior visual pathway lesions optical coherence tomography Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/c84d79c5673a424fad27fdc84c3f0f97
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spelling	oai:doaj.org-article:c84d79c5673a424fad27fdc84c3f0f972021-12-02T16:32:53ZQUANTIFICATION OF RETINAL NERVE FIBER LAYER FOR EARLY DETECTION OF ANTERIOR VISUAL PATHWAY LESIONS0030-96482411-884210.51253/pafmj.v71i1.3108https://doaj.org/article/c84d79c5673a424fad27fdc84c3f0f972021-02-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/3108https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To assess the role of quantification of retinal nerve fiber layer for early detection of anterior visual pathway lesions. Study Design: Case-control study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, from Jan to Jul 2019. Methodology: A total of 100 cases of anterior visual pathway lesions of varying clinical presentations were included in the study. There were 100 matched controls who were selected from the community without any ophthalmological abnormality using non-probability consecutive sampling technique. Retinal nerve fiber layer (RNFL) thickness was measured with the help of optical coherence tomography in both the cases and controls. Mean retinal nerve fiber layer values were compared in both the groups. Student’s t-test was applied to look for any significant difference between the two groups. Results: Mean age of the patients was 39.14 ± 3.925 years while mean age of the controls was 39.23 ± 2.415 years. Mean retinal nerve fiber layer thickness in the case group was 72.21 ± 9.615 µm while on the control group was 101.34 ± 9.615 µm. A statistically significant difference was observed between cases and controls in terms of mean retinal nerve fiber layer thickness (p<0.001). Subjects with retinal nerve fiber layer thickness <85 µm were more likely to exhibit anterior visual pathway lesions (OR= 15.915 [6.278-40.346]; 95% CI, p<0.001). Conclusion: Decreased retinal nerve fiber layer thickness can serve as a predictor for anterior visual pathway lesions. Optical coherence tomography should be incorporated for routine screening of high-risk cases in order.........Noureen MalikHannan MasudMuhammad Manzoor AwanArmy Medical College Rawalpindiarticleretinal nerve fiber layeranterior visual pathway lesionsoptical coherence tomographyMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss 1, Pp 96-100 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	retinal nerve fiber layer anterior visual pathway lesions optical coherence tomography Medicine R Medicine (General) R5-920
spellingShingle	retinal nerve fiber layer anterior visual pathway lesions optical coherence tomography Medicine R Medicine (General) R5-920 Noureen Malik Hannan Masud Muhammad Manzoor Awan QUANTIFICATION OF RETINAL NERVE FIBER LAYER FOR EARLY DETECTION OF ANTERIOR VISUAL PATHWAY LESIONS
description	Objective: To assess the role of quantification of retinal nerve fiber layer for early detection of anterior visual pathway lesions. Study Design: Case-control study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, from Jan to Jul 2019. Methodology: A total of 100 cases of anterior visual pathway lesions of varying clinical presentations were included in the study. There were 100 matched controls who were selected from the community without any ophthalmological abnormality using non-probability consecutive sampling technique. Retinal nerve fiber layer (RNFL) thickness was measured with the help of optical coherence tomography in both the cases and controls. Mean retinal nerve fiber layer values were compared in both the groups. Student’s t-test was applied to look for any significant difference between the two groups. Results: Mean age of the patients was 39.14 ± 3.925 years while mean age of the controls was 39.23 ± 2.415 years. Mean retinal nerve fiber layer thickness in the case group was 72.21 ± 9.615 µm while on the control group was 101.34 ± 9.615 µm. A statistically significant difference was observed between cases and controls in terms of mean retinal nerve fiber layer thickness (p<0.001). Subjects with retinal nerve fiber layer thickness <85 µm were more likely to exhibit anterior visual pathway lesions (OR= 15.915 [6.278-40.346]; 95% CI, p<0.001). Conclusion: Decreased retinal nerve fiber layer thickness can serve as a predictor for anterior visual pathway lesions. Optical coherence tomography should be incorporated for routine screening of high-risk cases in order.........
format	article
author	Noureen Malik Hannan Masud Muhammad Manzoor Awan
author_facet	Noureen Malik Hannan Masud Muhammad Manzoor Awan
author_sort	Noureen Malik
title	QUANTIFICATION OF RETINAL NERVE FIBER LAYER FOR EARLY DETECTION OF ANTERIOR VISUAL PATHWAY LESIONS
title_short	QUANTIFICATION OF RETINAL NERVE FIBER LAYER FOR EARLY DETECTION OF ANTERIOR VISUAL PATHWAY LESIONS
title_full	QUANTIFICATION OF RETINAL NERVE FIBER LAYER FOR EARLY DETECTION OF ANTERIOR VISUAL PATHWAY LESIONS
title_fullStr	QUANTIFICATION OF RETINAL NERVE FIBER LAYER FOR EARLY DETECTION OF ANTERIOR VISUAL PATHWAY LESIONS
title_full_unstemmed	QUANTIFICATION OF RETINAL NERVE FIBER LAYER FOR EARLY DETECTION OF ANTERIOR VISUAL PATHWAY LESIONS
title_sort	quantification of retinal nerve fiber layer for early detection of anterior visual pathway lesions
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doaj.org/article/c84d79c5673a424fad27fdc84c3f0f97
work_keys_str_mv	AT noureenmalik quantificationofretinalnervefiberlayerforearlydetectionofanteriorvisualpathwaylesions AT hannanmasud quantificationofretinalnervefiberlayerforearlydetectionofanteriorvisualpathwaylesions AT muhammadmanzoorawan quantificationofretinalnervefiberlayerforearlydetectionofanteriorvisualpathwaylesions
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QUANTIFICATION OF RETINAL NERVE FIBER LAYER FOR EARLY DETECTION OF ANTERIOR VISUAL PATHWAY LESIONS

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