The Atypical Occurrence of Two Biotin Protein Ligases in <named-content content-type="genus-species">Francisella novicida</named-content> Is Due to Distinct Roles in Virulence and Biotin Metabolism

The Atypical Occurrence of Two Biotin Protein Ligases in <named-content content-type="genus-species">Francisella novicida</named-content> Is Due to Distinct Roles in Virulence and Biotin Metabolism

ABSTRACT The physiological function of biotin requires biotin protein ligase activity in order to attach the coenzyme to its cognate proteins, which are enzymes involved in central metabolism. The model intracellular pathogen Francisella novicida is unusual in that it encodes two putative biotin pro...

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Autores principales: Youjun Feng, Chui-Yoke Chin, Vandana Chakravartty, Rongsui Gao, Emily K. Crispell, David S. Weiss, John E. Cronan
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/c852e019f2664b78b2937effd072db5e
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