Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry
The tumour microenvironment (TME) may change in response to cancer treatments such as KRAS G12C inhibition, with potential implications for combination therapies. Here, the authors provide an antibody panel and workflow for analysing the TME with imaging mass cytometry in pre-clinical mouse models.
Saved in:
Main Authors: | Febe van Maldegem, Karishma Valand, Megan Cole, Harshil Patel, Mihaela Angelova, Sareena Rana, Emma Colliver, Katey Enfield, Nourdine Bah, Gavin Kelly, Victoria Siu Kwan Tsang, Edurne Mugarza, Christopher Moore, Philip Hobson, Dina Levi, Miriam Molina-Arcas, Charles Swanton, Julian Downward |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/c85c11c742864408a99b5e94e13e53db |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Flow cytometry bioinformatics.
by: Kieran O'Neill, et al.
Published: (2013) -
Virtual-freezing fluorescence imaging flow cytometry
by: Hideharu Mikami, et al.
Published: (2020) -
Labeling Extracellular Vesicles for Nanoscale Flow Cytometry
by: Aizea Morales-Kastresana, et al.
Published: (2017) -
Flow Cytometry: A Blessing and a Curse
by: Hannah Drescher, et al.
Published: (2021) -
Computational Analysis of Microbial Flow Cytometry Data
by: Peter Rubbens, et al.
Published: (2021)