TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism

The PI3K/AKT signalling pathway regulates cancer metabolism. Here, the authors show a reciprocal positive feedback crosstalk between the PI3K/AKT and pentose phosphate pathway which promotes tumourigenesis.

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Detalles Bibliográficos
Autores principales:	Jie Cheng, Yan Huang, Xiaohui Zhang, Yue Yu, Shumin Wu, Jing Jiao, Linh Tran, Wanru Zhang, Ran Liu, Liuzhen Zhang, Mei Wang, Mengyao Wang, Wenyu Yan, Yilin Wu, Fangtao Chi, Peng Jiang, Xinxiang Zhang, Hong Wu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c8661cc145654943bf24870d56cc68e5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:c8661cc145654943bf24870d56cc68e52021-12-02T14:41:13ZTRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism10.1038/s41467-020-15819-32041-1723https://doaj.org/article/c8661cc145654943bf24870d56cc68e52020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15819-3https://doaj.org/toc/2041-1723The PI3K/AKT signalling pathway regulates cancer metabolism. Here, the authors show a reciprocal positive feedback crosstalk between the PI3K/AKT and pentose phosphate pathway which promotes tumourigenesis.Jie ChengYan HuangXiaohui ZhangYue YuShumin WuJing JiaoLinh TranWanru ZhangRan LiuLiuzhen ZhangMei WangMengyao WangWenyu YanYilin WuFangtao ChiPeng JiangXinxiang ZhangHong WuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jie Cheng Yan Huang Xiaohui Zhang Yue Yu Shumin Wu Jing Jiao Linh Tran Wanru Zhang Ran Liu Liuzhen Zhang Mei Wang Mengyao Wang Wenyu Yan Yilin Wu Fangtao Chi Peng Jiang Xinxiang Zhang Hong Wu TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism
description	The PI3K/AKT signalling pathway regulates cancer metabolism. Here, the authors show a reciprocal positive feedback crosstalk between the PI3K/AKT and pentose phosphate pathway which promotes tumourigenesis.
format	article
author	Jie Cheng Yan Huang Xiaohui Zhang Yue Yu Shumin Wu Jing Jiao Linh Tran Wanru Zhang Ran Liu Liuzhen Zhang Mei Wang Mengyao Wang Wenyu Yan Yilin Wu Fangtao Chi Peng Jiang Xinxiang Zhang Hong Wu
author_facet	Jie Cheng Yan Huang Xiaohui Zhang Yue Yu Shumin Wu Jing Jiao Linh Tran Wanru Zhang Ran Liu Liuzhen Zhang Mei Wang Mengyao Wang Wenyu Yan Yilin Wu Fangtao Chi Peng Jiang Xinxiang Zhang Hong Wu
author_sort	Jie Cheng
title	TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism
title_short	TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism
title_full	TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism
title_fullStr	TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism
title_full_unstemmed	TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism
title_sort	trim21 and phlda3 negatively regulate the crosstalk between the pi3k/akt pathway and ppp metabolism
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/c8661cc145654943bf24870d56cc68e5
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TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism

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