Sub-nanowatt resolution direct calorimetry for probing real-time metabolic activity of individual C. elegans worms

Calorimetry is widely used for metabolic studies, but measurements of single cells and small organisms are limited by the sensitivity of current techniques. Here the authors develop a sensitive platform for performing time-resolved metabolic measurements of single C. elegans worms from larval to adu...

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Autores principales: Sunghoon Hur, Rohith Mittapally, Swathi Yadlapalli, Pramod Reddy, Edgar Meyhofer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c87f5797704840d58c36a1ea16f70296
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Sumario:Calorimetry is widely used for metabolic studies, but measurements of single cells and small organisms are limited by the sensitivity of current techniques. Here the authors develop a sensitive platform for performing time-resolved metabolic measurements of single C. elegans worms from larval to adult stages.