The central role of NADPH depletion in MnTE-2-PyP-induced prostate cancer cell growth inhibition
Radiotherapy is commonly used in prostate cancer treatment. MnTE-2-PyP is a superoxide dismutase (SOD) mimic that can protect normal tissues from radiation toxicities while simultaneously promoting radiation-induced damage to cancer tissues. Previous work from our laboratory demonstrated that MnTE-2...
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Main Authors: | Yuxiang Zhu, Divya Murthy, Sai Sundeep Kollala, Elizabeth A. Kosmacek, Arpita Chatterjee, Joshua A. McDowell, Pankaj K. Singh, Rebecca E. Oberley-Deegan |
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Format: | article |
Language: | EN |
Published: |
Elsevier
2021
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Online Access: | https://doaj.org/article/c88a430211594c2db68f4a6a08566a9f |
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