Anesthesia technique and serum cytokine concentrations in the elective cesarean section

Background: Anesthesiologists should obtain the best technique for cesarean section (CS). This study designed to compare the effect of general anesthesia (GA) and spinal anesthesia (SA) on immune system function in elective CS. Materials and Methods: This descriptive study was performed on forty can...

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Autores principales:	Gholamhossein Hassanshahi, Maryam Hadavi, Abdollah Jafarzadeh, Mohsen Rezaeian, Reza Vazirinejad, Ali Sarkoohi, Fariba Aminzadeh
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	cesarean section cytokine general anesthesia interleukin spinal anesthesia Medicine R
Acceso en línea:	https://doaj.org/article/c88f0ea3653b4305b6c895ec47cd4d19
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spelling	oai:doaj.org-article:c88f0ea3653b4305b6c895ec47cd4d192021-11-12T10:25:23ZAnesthesia technique and serum cytokine concentrations in the elective cesarean section1735-19951735-713610.4103/jrms.JRMS_536_20https://doaj.org/article/c88f0ea3653b4305b6c895ec47cd4d192021-01-01T00:00:00Zhttp://www.jmsjournal.net/article.asp?issn=1735-1995;year=2021;volume=26;issue=1;spage=91;epage=91;aulast=Hassanshahihttps://doaj.org/toc/1735-1995https://doaj.org/toc/1735-7136Background: Anesthesiologists should obtain the best technique for cesarean section (CS). This study designed to compare the effect of general anesthesia (GA) and spinal anesthesia (SA) on immune system function in elective CS. Materials and Methods: This descriptive study was performed on forty candidates for elective CS. They were randomly divided into GA and SA groups. The serum concentrations of interleukin (IL)-4, IL-6, IL-10, and IL-17 and interferon-gamma (IFN-γ) were measured using ELISA method prior to anesthesia (T0), immediately after the uterine incision (T1), 2 h post CS (T2), and 24 h post CS (T3). Data were analyzed using descriptive statistics and Chi-square, independent t-test, and repeated measures. Results: No significant differences were observed between the GA and SA groups regarding the serum levels of IL-4, IL-6, IL-10, IL-17, and IFN-γ. The serum levels of transforming growth factor beta (TGF-β) in the SA group were significantly (P = 0.003) more than that of the GA group at T3. Conclusion: According to the angiogenesis properties of TGF-β, it seems that SA probably affects the rate of recovery more than that of the GA.Gholamhossein HassanshahiMaryam HadaviAbdollah JafarzadehMohsen RezaeianReza VazirinejadAli SarkoohiFariba AminzadehWolters Kluwer Medknow Publicationsarticlecesarean sectioncytokinegeneral anesthesiainterleukinspinal anesthesiaMedicineRENJournal of Research in Medical Sciences, Vol 26, Iss 1, Pp 91-91 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cesarean section cytokine general anesthesia interleukin spinal anesthesia Medicine R
spellingShingle	cesarean section cytokine general anesthesia interleukin spinal anesthesia Medicine R Gholamhossein Hassanshahi Maryam Hadavi Abdollah Jafarzadeh Mohsen Rezaeian Reza Vazirinejad Ali Sarkoohi Fariba Aminzadeh Anesthesia technique and serum cytokine concentrations in the elective cesarean section
description	Background: Anesthesiologists should obtain the best technique for cesarean section (CS). This study designed to compare the effect of general anesthesia (GA) and spinal anesthesia (SA) on immune system function in elective CS. Materials and Methods: This descriptive study was performed on forty candidates for elective CS. They were randomly divided into GA and SA groups. The serum concentrations of interleukin (IL)-4, IL-6, IL-10, and IL-17 and interferon-gamma (IFN-γ) were measured using ELISA method prior to anesthesia (T0), immediately after the uterine incision (T1), 2 h post CS (T2), and 24 h post CS (T3). Data were analyzed using descriptive statistics and Chi-square, independent t-test, and repeated measures. Results: No significant differences were observed between the GA and SA groups regarding the serum levels of IL-4, IL-6, IL-10, IL-17, and IFN-γ. The serum levels of transforming growth factor beta (TGF-β) in the SA group were significantly (P = 0.003) more than that of the GA group at T3. Conclusion: According to the angiogenesis properties of TGF-β, it seems that SA probably affects the rate of recovery more than that of the GA.
format	article
author	Gholamhossein Hassanshahi Maryam Hadavi Abdollah Jafarzadeh Mohsen Rezaeian Reza Vazirinejad Ali Sarkoohi Fariba Aminzadeh
author_facet	Gholamhossein Hassanshahi Maryam Hadavi Abdollah Jafarzadeh Mohsen Rezaeian Reza Vazirinejad Ali Sarkoohi Fariba Aminzadeh
author_sort	Gholamhossein Hassanshahi
title	Anesthesia technique and serum cytokine concentrations in the elective cesarean section
title_short	Anesthesia technique and serum cytokine concentrations in the elective cesarean section
title_full	Anesthesia technique and serum cytokine concentrations in the elective cesarean section
title_fullStr	Anesthesia technique and serum cytokine concentrations in the elective cesarean section
title_full_unstemmed	Anesthesia technique and serum cytokine concentrations in the elective cesarean section
title_sort	anesthesia technique and serum cytokine concentrations in the elective cesarean section
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/c88f0ea3653b4305b6c895ec47cd4d19
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Anesthesia technique and serum cytokine concentrations in the elective cesarean section

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