Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice

Cryptotanshinone (CPT), a natural quinoid diterpene, isolated from Salvia miltiorrhiza, has shown various pharmacological properties. However, its effect on chronic unpredictable stress (CUS)-induced depression phenotypes and the underlying mechanism remain unclear. Therefore, the aim of this study...

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Autores principales: Wang Kaixin, Zhai Qingling, Wang Sanwang, Li Qiongyu, Liu Jing, Meng Fantao, Wang Wentao, Zhang Jinjie, Wang Dan, Zhao Di, Liu Cuilan, Dai Juanjuan, Li Chen, Cui Minghu, Chen Jinbo
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2021
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Acceso en línea:https://doaj.org/article/c89ef6bd6b7d4da991f44e4049713ab2
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Sumario:Cryptotanshinone (CPT), a natural quinoid diterpene, isolated from Salvia miltiorrhiza, has shown various pharmacological properties. However, its effect on chronic unpredictable stress (CUS)-induced depression phenotypes and the underlying mechanism remain unclear. Therefore, the aim of this study was to investigate whether CPT could exert an antidepressant effect.