Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice

Cryptotanshinone (CPT), a natural quinoid diterpene, isolated from Salvia miltiorrhiza, has shown various pharmacological properties. However, its effect on chronic unpredictable stress (CUS)-induced depression phenotypes and the underlying mechanism remain unclear. Therefore, the aim of this study...

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Autores principales:	Wang Kaixin, Zhai Qingling, Wang Sanwang, Li Qiongyu, Liu Jing, Meng Fantao, Wang Wentao, Zhang Jinjie, Wang Dan, Zhao Di, Liu Cuilan, Dai Juanjuan, Li Chen, Cui Minghu, Chen Jinbo
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	cryptotanshinone depression neuroinflammation microglial polarization neurogenesis bdnf Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Acceso en línea:	https://doaj.org/article/c89ef6bd6b7d4da991f44e4049713ab2
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spelling	oai:doaj.org-article:c89ef6bd6b7d4da991f44e4049713ab22021-12-05T14:11:05ZCryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice2081-693610.1515/tnsci-2020-0198https://doaj.org/article/c89ef6bd6b7d4da991f44e4049713ab22021-11-01T00:00:00Zhttps://doi.org/10.1515/tnsci-2020-0198https://doaj.org/toc/2081-6936Cryptotanshinone (CPT), a natural quinoid diterpene, isolated from Salvia miltiorrhiza, has shown various pharmacological properties. However, its effect on chronic unpredictable stress (CUS)-induced depression phenotypes and the underlying mechanism remain unclear. Therefore, the aim of this study was to investigate whether CPT could exert an antidepressant effect.Wang KaixinZhai QinglingWang SanwangLi QiongyuLiu JingMeng FantaoWang WentaoZhang JinjieWang DanZhao DiLiu CuilanDai JuanjuanLi ChenCui MinghuChen JinboDe Gruyterarticlecryptotanshinonedepressionneuroinflammationmicroglial polarizationneurogenesisbdnfNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571ENTranslational Neuroscience, Vol 12, Iss 1, Pp 469-481 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cryptotanshinone depression neuroinflammation microglial polarization neurogenesis bdnf Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
spellingShingle	cryptotanshinone depression neuroinflammation microglial polarization neurogenesis bdnf Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Wang Kaixin Zhai Qingling Wang Sanwang Li Qiongyu Liu Jing Meng Fantao Wang Wentao Zhang Jinjie Wang Dan Zhao Di Liu Cuilan Dai Juanjuan Li Chen Cui Minghu Chen Jinbo Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice
description	Cryptotanshinone (CPT), a natural quinoid diterpene, isolated from Salvia miltiorrhiza, has shown various pharmacological properties. However, its effect on chronic unpredictable stress (CUS)-induced depression phenotypes and the underlying mechanism remain unclear. Therefore, the aim of this study was to investigate whether CPT could exert an antidepressant effect.
format	article
author	Wang Kaixin Zhai Qingling Wang Sanwang Li Qiongyu Liu Jing Meng Fantao Wang Wentao Zhang Jinjie Wang Dan Zhao Di Liu Cuilan Dai Juanjuan Li Chen Cui Minghu Chen Jinbo
author_facet	Wang Kaixin Zhai Qingling Wang Sanwang Li Qiongyu Liu Jing Meng Fantao Wang Wentao Zhang Jinjie Wang Dan Zhao Di Liu Cuilan Dai Juanjuan Li Chen Cui Minghu Chen Jinbo
author_sort	Wang Kaixin
title	Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice
title_short	Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice
title_full	Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice
title_fullStr	Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice
title_full_unstemmed	Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice
title_sort	cryptotanshinone ameliorates cus-induced depressive-like behaviors in mice
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/c89ef6bd6b7d4da991f44e4049713ab2
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Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice

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