Acute myocardial infarction with left main coronary artery ostial negative remodelling as the first manifestation of Takayasu arteritis: a case report

Abstract Background Takayasu arteritis is a chronic inflammatory disease involving the aorta and its major branches. Acute myocardial infarction rarely but not so much presents in patients with Takayasu arteritis, and the preferable revascularization strategy is still under debate. Case presentation...

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Autores principales: Shiqiang Zhou, Chao Gao, Fei Li
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Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/c8a118ed5fa94f0b96b495b980f48966
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spelling oai:doaj.org-article:c8a118ed5fa94f0b96b495b980f489662021-11-28T12:05:22ZAcute myocardial infarction with left main coronary artery ostial negative remodelling as the first manifestation of Takayasu arteritis: a case report10.1186/s12872-021-02376-w1471-2261https://doaj.org/article/c8a118ed5fa94f0b96b495b980f489662021-11-01T00:00:00Zhttps://doi.org/10.1186/s12872-021-02376-whttps://doaj.org/toc/1471-2261Abstract Background Takayasu arteritis is a chronic inflammatory disease involving the aorta and its major branches. Acute myocardial infarction rarely but not so much presents in patients with Takayasu arteritis, and the preferable revascularization strategy is still under debate. Case presentation A 22-year-old female with Takayasu arteritis presented with acute myocardial infarction. Coronary angiography and intravenous ultrasound (IVUS) showed that the right coronary artery (RCA) was occluded and that there was severe negative remodelling at the ostium of the left main coronary artery (LMCA). The patient was treated by primary percutaneous transluminal coronary angioplasty (PTCA) with a scoring balloon in the LMCA, without stent implantation. After 3 months of immunosuppressive medication, the patient received RCA revascularization by stenting. There was progressive external elastic membrane (EEM) enlargement of the LMCA ostium demonstrated by IVUS at 3 and 15 months post-initial PTCA. Conclusion Here, we report a case of Takayasu arteritis with involvement of the coronary artery ostium. Through PTCA and long-term immunosuppressive medication, we found that coronary negative remodelling might be reversible in patients with Takayasu arteritis.Shiqiang ZhouChao GaoFei LiBMCarticleCoronary arteryNegative remodellingTakayasu arteritisIntravenous ultrasoundCase reportDiseases of the circulatory (Cardiovascular) systemRC666-701ENBMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-6 (2021)
institution DOAJ
collection DOAJ
language EN
topic Coronary artery
Negative remodelling
Takayasu arteritis
Intravenous ultrasound
Case report
Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Coronary artery
Negative remodelling
Takayasu arteritis
Intravenous ultrasound
Case report
Diseases of the circulatory (Cardiovascular) system
RC666-701
Shiqiang Zhou
Chao Gao
Fei Li
Acute myocardial infarction with left main coronary artery ostial negative remodelling as the first manifestation of Takayasu arteritis: a case report
description Abstract Background Takayasu arteritis is a chronic inflammatory disease involving the aorta and its major branches. Acute myocardial infarction rarely but not so much presents in patients with Takayasu arteritis, and the preferable revascularization strategy is still under debate. Case presentation A 22-year-old female with Takayasu arteritis presented with acute myocardial infarction. Coronary angiography and intravenous ultrasound (IVUS) showed that the right coronary artery (RCA) was occluded and that there was severe negative remodelling at the ostium of the left main coronary artery (LMCA). The patient was treated by primary percutaneous transluminal coronary angioplasty (PTCA) with a scoring balloon in the LMCA, without stent implantation. After 3 months of immunosuppressive medication, the patient received RCA revascularization by stenting. There was progressive external elastic membrane (EEM) enlargement of the LMCA ostium demonstrated by IVUS at 3 and 15 months post-initial PTCA. Conclusion Here, we report a case of Takayasu arteritis with involvement of the coronary artery ostium. Through PTCA and long-term immunosuppressive medication, we found that coronary negative remodelling might be reversible in patients with Takayasu arteritis.
format article
author Shiqiang Zhou
Chao Gao
Fei Li
author_facet Shiqiang Zhou
Chao Gao
Fei Li
author_sort Shiqiang Zhou
title Acute myocardial infarction with left main coronary artery ostial negative remodelling as the first manifestation of Takayasu arteritis: a case report
title_short Acute myocardial infarction with left main coronary artery ostial negative remodelling as the first manifestation of Takayasu arteritis: a case report
title_full Acute myocardial infarction with left main coronary artery ostial negative remodelling as the first manifestation of Takayasu arteritis: a case report
title_fullStr Acute myocardial infarction with left main coronary artery ostial negative remodelling as the first manifestation of Takayasu arteritis: a case report
title_full_unstemmed Acute myocardial infarction with left main coronary artery ostial negative remodelling as the first manifestation of Takayasu arteritis: a case report
title_sort acute myocardial infarction with left main coronary artery ostial negative remodelling as the first manifestation of takayasu arteritis: a case report
publisher BMC
publishDate 2021
url https://doaj.org/article/c8a118ed5fa94f0b96b495b980f48966
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AT chaogao acutemyocardialinfarctionwithleftmaincoronaryarteryostialnegativeremodellingasthefirstmanifestationoftakayasuarteritisacasereport
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