The use of dry amniotic membrane in pterygium surgery

Gelareh S Noureddin, Sonia N Yeung Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada Abstract: Pterygium is a fibrovascular growth of the bulbar conjunctiva that crosses the limbus and extends over the peripheral cornea, in some cases resulting...

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Autores principales:	Noureddin GS, Yeung SN
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	cornea pterygium amniotic membrane conjunctival autograft Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/c8a3b1d1e0894606810132945209a2fa
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spelling	oai:doaj.org-article:c8a3b1d1e0894606810132945209a2fa2021-12-02T04:23:39ZThe use of dry amniotic membrane in pterygium surgery1177-5483https://doaj.org/article/c8a3b1d1e0894606810132945209a2fa2016-04-01T00:00:00Zhttps://www.dovepress.com/the-use-of-dry-amniotic-membrane-in-pterygium-surgery-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Gelareh S Noureddin, Sonia N Yeung Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada Abstract: Pterygium is a fibrovascular growth of the bulbar conjunctiva that crosses the limbus and extends over the peripheral cornea, in some cases resulting in significant visual morbidity. When treatment is indicated, surgery is necessary, and several management options exist. These include excision, conjunctival autografting, and the use of adjuvant therapies. This paper reviews the incidence and prevalence of pterygia and also describes the various techniques currently used to treat this condition. These management options are compared to the use of dry amniotic membrane grafting (AMG), specifically with regard to recurrence rates, time to recurrence, safety and tolerability, as well as patient factors including cosmesis and quality of life. AMG has been used in the treatment of ocular surface disease due to a variety of benefits, including its anti-inflammatory properties, as well as its ability to promote epithelial growth and suppress transforming growth factor-β signaling and fibroblast proliferation. However, rates of recurrence for AMG following pterygium excision still surpass other commonly used techniques, including conjunctival and limbal autografting. Nevertheless, there are circumstances in which AMG may be most beneficial to the patient, such as when preexisting conjunctival scarring is present, when the conjunctiva must be spared for future glaucoma filtering surgery, or in cases of large or double-headed pterygia. Therefore, surgeons should be prepared to offer this procedure as an option to their patients for the treatment of pterygia. Keywords: cornea, pterygium, amniotic membrane, conjunctival autograftNoureddin GSYeung SNDove Medical Pressarticlecorneapterygiumamniotic membraneconjunctival autograftOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 705-712 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	cornea pterygium amniotic membrane conjunctival autograft Ophthalmology RE1-994
spellingShingle	cornea pterygium amniotic membrane conjunctival autograft Ophthalmology RE1-994 Noureddin GS Yeung SN The use of dry amniotic membrane in pterygium surgery
description	Gelareh S Noureddin, Sonia N Yeung Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada Abstract: Pterygium is a fibrovascular growth of the bulbar conjunctiva that crosses the limbus and extends over the peripheral cornea, in some cases resulting in significant visual morbidity. When treatment is indicated, surgery is necessary, and several management options exist. These include excision, conjunctival autografting, and the use of adjuvant therapies. This paper reviews the incidence and prevalence of pterygia and also describes the various techniques currently used to treat this condition. These management options are compared to the use of dry amniotic membrane grafting (AMG), specifically with regard to recurrence rates, time to recurrence, safety and tolerability, as well as patient factors including cosmesis and quality of life. AMG has been used in the treatment of ocular surface disease due to a variety of benefits, including its anti-inflammatory properties, as well as its ability to promote epithelial growth and suppress transforming growth factor-β signaling and fibroblast proliferation. However, rates of recurrence for AMG following pterygium excision still surpass other commonly used techniques, including conjunctival and limbal autografting. Nevertheless, there are circumstances in which AMG may be most beneficial to the patient, such as when preexisting conjunctival scarring is present, when the conjunctiva must be spared for future glaucoma filtering surgery, or in cases of large or double-headed pterygia. Therefore, surgeons should be prepared to offer this procedure as an option to their patients for the treatment of pterygia. Keywords: cornea, pterygium, amniotic membrane, conjunctival autograft
format	article
author	Noureddin GS Yeung SN
author_facet	Noureddin GS Yeung SN
author_sort	Noureddin GS
title	The use of dry amniotic membrane in pterygium surgery
title_short	The use of dry amniotic membrane in pterygium surgery
title_full	The use of dry amniotic membrane in pterygium surgery
title_fullStr	The use of dry amniotic membrane in pterygium surgery
title_full_unstemmed	The use of dry amniotic membrane in pterygium surgery
title_sort	use of dry amniotic membrane in pterygium surgery
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/c8a3b1d1e0894606810132945209a2fa
work_keys_str_mv	AT noureddings theuseofdryamnioticmembraneinpterygiumsurgery AT yeungsn theuseofdryamnioticmembraneinpterygiumsurgery AT noureddings useofdryamnioticmembraneinpterygiumsurgery AT yeungsn useofdryamnioticmembraneinpterygiumsurgery
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The use of dry amniotic membrane in pterygium surgery

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