A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein.

Apolipoprotein B-containing lipoproteins (B-lps) are essential for the transport of hydrophobic dietary and endogenous lipids through the circulation in vertebrates. Zebrafish embryos produce large numbers of B-lps in the yolk syncytial layer (YSL) to move lipids from yolk to growing tissues. Disrup...

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Auteurs principaux: Meredith H Wilson, Sujith Rajan, Aidan Danoff, Richard J White, Monica R Hensley, Vanessa H Quinlivan, Rosario Recacha, James H Thierer, Frederick J Tan, Elisabeth M Busch-Nentwich, Lloyd Ruddock, M Mahmood Hussain, Steven A Farber
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2020
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Accès en ligne:https://doaj.org/article/c8a3fa12b57c47668859e647c2dbd300
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