$Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids$
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Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids

Latex, a sticky emulsion produced by specialized cells called laticifers, is a crucial part of a plant’s defense system against herbivory and pathogens. It consists of a broad spectrum of active compounds, which are beneficial not only for plants, but for human health as well, enough to mention the...

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Autores principales:	Joanna Gracz-Bernaciak, Oliwia Mazur, Robert Nawrot
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	latex antiviral proteins antimicrobial compounds cytotoxicity drug discovery <i>Chelidonium majus</i> Biology (General) QH301-705.5 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/c8b2b0e632d04743ba024213d12d36b1
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spelling	oai:doaj.org-article:c8b2b0e632d04743ba024213d12d36b12021-11-25T17:56:33ZFunctional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids10.3390/ijms2222124271422-00671661-6596https://doaj.org/article/c8b2b0e632d04743ba024213d12d36b12021-11-01T00:00:00Zhttps://www.mdpi.com/1422-0067/22/22/12427https://doaj.org/toc/1661-6596https://doaj.org/toc/1422-0067Latex, a sticky emulsion produced by specialized cells called laticifers, is a crucial part of a plant’s defense system against herbivory and pathogens. It consists of a broad spectrum of active compounds, which are beneficial not only for plants, but for human health as well, enough to mention the use of morphine or codeine from poppy latex. Here, we reviewed latex’s general role in plant physiology and the significance of particular compounds (alkaloids and proteins) to its defense system with the example of <i>Chelidonium majus</i> L. from the poppy family. We further attempt to present latex chemicals used so far in medicine and then focus on functional studies of proteins and other compounds with potential pharmacological activities using modern techniques such as CRISPR/Cas9 gene editing. Despite the centuries-old tradition of using latex-bearing plants in therapies, there are still a lot of promising molecules waiting to be explored.Joanna Gracz-BernaciakOliwia MazurRobert NawrotMDPI AGarticlelatexantiviral proteinsantimicrobial compoundscytotoxicitydrug discovery<i>Chelidonium majus</i>Biology (General)QH301-705.5ChemistryQD1-999ENInternational Journal of Molecular Sciences, Vol 22, Iss 12427, p 12427 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	latex antiviral proteins antimicrobial compounds cytotoxicity drug discovery <i>Chelidonium majus</i> Biology (General) QH301-705.5 Chemistry QD1-999
spellingShingle	latex antiviral proteins antimicrobial compounds cytotoxicity drug discovery <i>Chelidonium majus</i> Biology (General) QH301-705.5 Chemistry QD1-999 Joanna Gracz-Bernaciak Oliwia Mazur Robert Nawrot Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids
description	Latex, a sticky emulsion produced by specialized cells called laticifers, is a crucial part of a plant’s defense system against herbivory and pathogens. It consists of a broad spectrum of active compounds, which are beneficial not only for plants, but for human health as well, enough to mention the use of morphine or codeine from poppy latex. Here, we reviewed latex’s general role in plant physiology and the significance of particular compounds (alkaloids and proteins) to its defense system with the example of <i>Chelidonium majus</i> L. from the poppy family. We further attempt to present latex chemicals used so far in medicine and then focus on functional studies of proteins and other compounds with potential pharmacological activities using modern techniques such as CRISPR/Cas9 gene editing. Despite the centuries-old tradition of using latex-bearing plants in therapies, there are still a lot of promising molecules waiting to be explored.
format	article
author	Joanna Gracz-Bernaciak Oliwia Mazur Robert Nawrot
author_facet	Joanna Gracz-Bernaciak Oliwia Mazur Robert Nawrot
author_sort	Joanna Gracz-Bernaciak
title	Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids
title_short	Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids
title_full	Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids
title_fullStr	Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids
title_full_unstemmed	Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids
title_sort	functional studies of plant latex as a rich source of bioactive compounds: focus on proteins and alkaloids
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/c8b2b0e632d04743ba024213d12d36b1
work_keys_str_mv	AT joannagraczbernaciak functionalstudiesofplantlatexasarichsourceofbioactivecompoundsfocusonproteinsandalkaloids AT oliwiamazur functionalstudiesofplantlatexasarichsourceofbioactivecompoundsfocusonproteinsandalkaloids AT robertnawrot functionalstudiesofplantlatexasarichsourceofbioactivecompoundsfocusonproteinsandalkaloids
_version_	1718411829333458944

Functional Studies of Plant Latex as a Rich Source of Bioactive Compounds: Focus on Proteins and Alkaloids

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