Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans

Okabe et al. show that the miRNA production system in the neuron and the small RNA transport machinery in the intestine are required for the acquisition of hormesis. For its inheritance, both the transport of small RNAs in the germline and the germline Argonaute HRDE-1 complex are needed, highlighti...

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Autores principales: Emiko Okabe, Masaharu Uno, Saya Kishimoto, Eisuke Nishida
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c8b4e77b94f946d6bef7dc612bea48de
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spelling oai:doaj.org-article:c8b4e77b94f946d6bef7dc612bea48de2021-12-02T14:03:56ZIntertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans10.1038/s42003-021-01692-32399-3642https://doaj.org/article/c8b4e77b94f946d6bef7dc612bea48de2021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01692-3https://doaj.org/toc/2399-3642Okabe et al. show that the miRNA production system in the neuron and the small RNA transport machinery in the intestine are required for the acquisition of hormesis. For its inheritance, both the transport of small RNAs in the germline and the germline Argonaute HRDE-1 complex are needed, highlighting distinct contribution of small RNA systems to hormesis.Emiko OkabeMasaharu UnoSaya KishimotoEisuke NishidaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Emiko Okabe
Masaharu Uno
Saya Kishimoto
Eisuke Nishida
Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans
description Okabe et al. show that the miRNA production system in the neuron and the small RNA transport machinery in the intestine are required for the acquisition of hormesis. For its inheritance, both the transport of small RNAs in the germline and the germline Argonaute HRDE-1 complex are needed, highlighting distinct contribution of small RNA systems to hormesis.
format article
author Emiko Okabe
Masaharu Uno
Saya Kishimoto
Eisuke Nishida
author_facet Emiko Okabe
Masaharu Uno
Saya Kishimoto
Eisuke Nishida
author_sort Emiko Okabe
title Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans
title_short Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans
title_full Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans
title_fullStr Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans
title_full_unstemmed Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans
title_sort intertissue small rna communication mediates the acquisition and inheritance of hormesis in caenorhabditis elegans
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c8b4e77b94f946d6bef7dc612bea48de
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AT masaharuuno intertissuesmallrnacommunicationmediatestheacquisitionandinheritanceofhormesisincaenorhabditiselegans
AT sayakishimoto intertissuesmallrnacommunicationmediatestheacquisitionandinheritanceofhormesisincaenorhabditiselegans
AT eisukenishida intertissuesmallrnacommunicationmediatestheacquisitionandinheritanceofhormesisincaenorhabditiselegans
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