Voltage gating of mechanosensitive PIEZO channels

PIEZO proteins form mechanosensitive ion channels. Here the authors present electrophysiological measurements that show that PIEZO channels are also modulated by voltage and can switch to a purely voltage gated mode, which is an evolutionary conserved property of this channel family.

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Bibliographic Details
Main Authors:	Mirko Moroni, M. Rocio Servin-Vences, Raluca Fleischer, Oscar Sánchez-Carranza, Gary R. Lewin
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/c8b799ea4464428ebbdd91025a26f225
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spelling	oai:doaj.org-article:c8b799ea4464428ebbdd91025a26f2252021-12-02T17:31:13ZVoltage gating of mechanosensitive PIEZO channels10.1038/s41467-018-03502-72041-1723https://doaj.org/article/c8b799ea4464428ebbdd91025a26f2252018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03502-7https://doaj.org/toc/2041-1723PIEZO proteins form mechanosensitive ion channels. Here the authors present electrophysiological measurements that show that PIEZO channels are also modulated by voltage and can switch to a purely voltage gated mode, which is an evolutionary conserved property of this channel family.Mirko MoroniM. Rocio Servin-VencesRaluca FleischerOscar Sánchez-CarranzaGary R. LewinNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mirko Moroni M. Rocio Servin-Vences Raluca Fleischer Oscar Sánchez-Carranza Gary R. Lewin Voltage gating of mechanosensitive PIEZO channels
description	PIEZO proteins form mechanosensitive ion channels. Here the authors present electrophysiological measurements that show that PIEZO channels are also modulated by voltage and can switch to a purely voltage gated mode, which is an evolutionary conserved property of this channel family.
format	article
author	Mirko Moroni M. Rocio Servin-Vences Raluca Fleischer Oscar Sánchez-Carranza Gary R. Lewin
author_facet	Mirko Moroni M. Rocio Servin-Vences Raluca Fleischer Oscar Sánchez-Carranza Gary R. Lewin
author_sort	Mirko Moroni
title	Voltage gating of mechanosensitive PIEZO channels
title_short	Voltage gating of mechanosensitive PIEZO channels
title_full	Voltage gating of mechanosensitive PIEZO channels
title_fullStr	Voltage gating of mechanosensitive PIEZO channels
title_full_unstemmed	Voltage gating of mechanosensitive PIEZO channels
title_sort	voltage gating of mechanosensitive piezo channels
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c8b799ea4464428ebbdd91025a26f225
work_keys_str_mv	AT mirkomoroni voltagegatingofmechanosensitivepiezochannels AT mrocioservinvences voltagegatingofmechanosensitivepiezochannels AT ralucafleischer voltagegatingofmechanosensitivepiezochannels AT oscarsanchezcarranza voltagegatingofmechanosensitivepiezochannels AT garyrlewin voltagegatingofmechanosensitivepiezochannels
_version_	1718380699863482368

Voltage gating of mechanosensitive PIEZO channels

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