ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics

The cytoskeleton plays a key role in cell/cell junction formation, but how the coordinated behaviour of the cytoskeleton contributes is not known. Here the authors show that actin-microtubule crosslinker ACF7 plays a key role in tight junction stabilization and wound healing in intestinal epithelium...

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Autores principales:	Yanlei Ma, Jiping Yue, Yao Zhang, Chenzhang Shi, Matt Odenwald, Wenguang G. Liang, Qing Wei, Ajay Goel, Xuewen Gou, Jamie Zhang, Shao-Yu Chen, Wei-Jen Tang, Jerrold R. Turner, Feng Yang, Hong Liang, Huanlong Qin, Xiaoyang Wu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c8c2b37e2d3f4afba906bc428a635587
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spelling	oai:doaj.org-article:c8c2b37e2d3f4afba906bc428a6355872021-12-02T14:42:23ZACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics10.1038/ncomms153752041-1723https://doaj.org/article/c8c2b37e2d3f4afba906bc428a6355872017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15375https://doaj.org/toc/2041-1723The cytoskeleton plays a key role in cell/cell junction formation, but how the coordinated behaviour of the cytoskeleton contributes is not known. Here the authors show that actin-microtubule crosslinker ACF7 plays a key role in tight junction stabilization and wound healing in intestinal epithelium.Yanlei MaJiping YueYao ZhangChenzhang ShiMatt OdenwaldWenguang G. LiangQing WeiAjay GoelXuewen GouJamie ZhangShao-Yu ChenWei-Jen TangJerrold R. TurnerFeng YangHong LiangHuanlong QinXiaoyang WuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yanlei Ma Jiping Yue Yao Zhang Chenzhang Shi Matt Odenwald Wenguang G. Liang Qing Wei Ajay Goel Xuewen Gou Jamie Zhang Shao-Yu Chen Wei-Jen Tang Jerrold R. Turner Feng Yang Hong Liang Huanlong Qin Xiaoyang Wu ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics
description	The cytoskeleton plays a key role in cell/cell junction formation, but how the coordinated behaviour of the cytoskeleton contributes is not known. Here the authors show that actin-microtubule crosslinker ACF7 plays a key role in tight junction stabilization and wound healing in intestinal epithelium.
format	article
author	Yanlei Ma Jiping Yue Yao Zhang Chenzhang Shi Matt Odenwald Wenguang G. Liang Qing Wei Ajay Goel Xuewen Gou Jamie Zhang Shao-Yu Chen Wei-Jen Tang Jerrold R. Turner Feng Yang Hong Liang Huanlong Qin Xiaoyang Wu
author_facet	Yanlei Ma Jiping Yue Yao Zhang Chenzhang Shi Matt Odenwald Wenguang G. Liang Qing Wei Ajay Goel Xuewen Gou Jamie Zhang Shao-Yu Chen Wei-Jen Tang Jerrold R. Turner Feng Yang Hong Liang Huanlong Qin Xiaoyang Wu
author_sort	Yanlei Ma
title	ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics
title_short	ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics
title_full	ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics
title_fullStr	ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics
title_full_unstemmed	ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics
title_sort	acf7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/c8c2b37e2d3f4afba906bc428a635587
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ACF7 regulates inflammatory colitis and intestinal wound response by orchestrating tight junction dynamics

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