Senescent cell turnover slows with age providing an explanation for the Gompertz law

One of the underlying causes of aging is the accumulation of senescent cells, but their turnover rates and dynamics during ageing are unknown. Here the authors measure and model senescent cell production and removal and explore implications for mortality.

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Bibliographic Details
Main Authors: Omer Karin, Amit Agrawal, Ziv Porat, Valery Krizhanovsky, Uri Alon
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/c8d1148874e54b7f9c4cf46bb629afe1
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