GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections

Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in neuronal systems, but the potential role for such neurotransmitters on the immune system are emerging. Here the authors show GABA signaling is linked to autophagy, enhancing the host response against intracellular bacteria.

Guardado en:

Detalles Bibliográficos
Autores principales:	Jin Kyung Kim, Yi Sak Kim, Hye-Mi Lee, Hyo Sun Jin, Chiranjivi Neupane, Sup Kim, Sang-Hee Lee, Jung-Joon Min, Miwa Sasai, Jae-Ho Jeong, Seong-Kyu Choe, Jin-Man Kim, Masahiro Yamamoto, Hyon E. Choy, Jin Bong Park, Eun-Kyeong Jo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c8d77fa23b514ad384c99df5991f346a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c8d77fa23b514ad384c99df5991f346a
record_format	dspace
spelling	oai:doaj.org-article:c8d77fa23b514ad384c99df5991f346a2021-12-02T15:33:37ZGABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections10.1038/s41467-018-06487-52041-1723https://doaj.org/article/c8d77fa23b514ad384c99df5991f346a2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06487-5https://doaj.org/toc/2041-1723Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in neuronal systems, but the potential role for such neurotransmitters on the immune system are emerging. Here the authors show GABA signaling is linked to autophagy, enhancing the host response against intracellular bacteria.Jin Kyung KimYi Sak KimHye-Mi LeeHyo Sun JinChiranjivi NeupaneSup KimSang-Hee LeeJung-Joon MinMiwa SasaiJae-Ho JeongSeong-Kyu ChoeJin-Man KimMasahiro YamamotoHyon E. ChoyJin Bong ParkEun-Kyeong JoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jin Kyung Kim Yi Sak Kim Hye-Mi Lee Hyo Sun Jin Chiranjivi Neupane Sup Kim Sang-Hee Lee Jung-Joon Min Miwa Sasai Jae-Ho Jeong Seong-Kyu Choe Jin-Man Kim Masahiro Yamamoto Hyon E. Choy Jin Bong Park Eun-Kyeong Jo GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections
description	Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in neuronal systems, but the potential role for such neurotransmitters on the immune system are emerging. Here the authors show GABA signaling is linked to autophagy, enhancing the host response against intracellular bacteria.
format	article
author	Jin Kyung Kim Yi Sak Kim Hye-Mi Lee Hyo Sun Jin Chiranjivi Neupane Sup Kim Sang-Hee Lee Jung-Joon Min Miwa Sasai Jae-Ho Jeong Seong-Kyu Choe Jin-Man Kim Masahiro Yamamoto Hyon E. Choy Jin Bong Park Eun-Kyeong Jo
author_facet	Jin Kyung Kim Yi Sak Kim Hye-Mi Lee Hyo Sun Jin Chiranjivi Neupane Sup Kim Sang-Hee Lee Jung-Joon Min Miwa Sasai Jae-Ho Jeong Seong-Kyu Choe Jin-Man Kim Masahiro Yamamoto Hyon E. Choy Jin Bong Park Eun-Kyeong Jo
author_sort	Jin Kyung Kim
title	GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections
title_short	GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections
title_full	GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections
title_fullStr	GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections
title_full_unstemmed	GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections
title_sort	gabaergic signaling linked to autophagy enhances host protection against intracellular bacterial infections
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/c8d77fa23b514ad384c99df5991f346a
work_keys_str_mv	AT jinkyungkim gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT yisakkim gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT hyemilee gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT hyosunjin gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT chiranjivineupane gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT supkim gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT sangheelee gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT jungjoonmin gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT miwasasai gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT jaehojeong gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT seongkyuchoe gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT jinmankim gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT masahiroyamamoto gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT hyonechoy gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT jinbongpark gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections AT eunkyeongjo gabaergicsignalinglinkedtoautophagyenhanceshostprotectionagainstintracellularbacterialinfections
_version_	1718387107756507136

GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections

Ejemplares similares