Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect

Projections from the anterior and posterior basolateral amygdala (pBLA) to the ventral hippocampus CA1 (vCA1) are heterogenous. Here the authors show that activating the pathway from pBLA to vCA1 calbindin 1 positive neurons has an anxiolytic effect in approach-avoidance tasks in mice.

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Autores principales: Guilin Pi, Di Gao, Dongqin Wu, Yali Wang, Huiyang Lei, Wenbo Zeng, Yang Gao, Huiling Yu, Rui Xiong, Tao Jiang, Shihong Li, Xin Wang, Jing Guo, Si Zhang, Taoyuan Yin, Ting He, Dan Ke, Ruining Li, Honglian Li, Gongping Liu, Xifei Yang, Min–Hua Luo, Xiaohui Zhang, Ying Yang, Jian–Zhi Wang
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c8dce64f4e8c49f1836109d3e2d14530
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spelling oai:doaj.org-article:c8dce64f4e8c49f1836109d3e2d145302021-12-02T14:41:27ZPosterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect10.1038/s41467-019-13919-32041-1723https://doaj.org/article/c8dce64f4e8c49f1836109d3e2d145302020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13919-3https://doaj.org/toc/2041-1723Projections from the anterior and posterior basolateral amygdala (pBLA) to the ventral hippocampus CA1 (vCA1) are heterogenous. Here the authors show that activating the pathway from pBLA to vCA1 calbindin 1 positive neurons has an anxiolytic effect in approach-avoidance tasks in mice.Guilin PiDi GaoDongqin WuYali WangHuiyang LeiWenbo ZengYang GaoHuiling YuRui XiongTao JiangShihong LiXin WangJing GuoSi ZhangTaoyuan YinTing HeDan KeRuining LiHonglian LiGongping LiuXifei YangMin–Hua LuoXiaohui ZhangYing YangJian–Zhi WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Guilin Pi
Di Gao
Dongqin Wu
Yali Wang
Huiyang Lei
Wenbo Zeng
Yang Gao
Huiling Yu
Rui Xiong
Tao Jiang
Shihong Li
Xin Wang
Jing Guo
Si Zhang
Taoyuan Yin
Ting He
Dan Ke
Ruining Li
Honglian Li
Gongping Liu
Xifei Yang
Min–Hua Luo
Xiaohui Zhang
Ying Yang
Jian–Zhi Wang
Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect
description Projections from the anterior and posterior basolateral amygdala (pBLA) to the ventral hippocampus CA1 (vCA1) are heterogenous. Here the authors show that activating the pathway from pBLA to vCA1 calbindin 1 positive neurons has an anxiolytic effect in approach-avoidance tasks in mice.
format article
author Guilin Pi
Di Gao
Dongqin Wu
Yali Wang
Huiyang Lei
Wenbo Zeng
Yang Gao
Huiling Yu
Rui Xiong
Tao Jiang
Shihong Li
Xin Wang
Jing Guo
Si Zhang
Taoyuan Yin
Ting He
Dan Ke
Ruining Li
Honglian Li
Gongping Liu
Xifei Yang
Min–Hua Luo
Xiaohui Zhang
Ying Yang
Jian–Zhi Wang
author_facet Guilin Pi
Di Gao
Dongqin Wu
Yali Wang
Huiyang Lei
Wenbo Zeng
Yang Gao
Huiling Yu
Rui Xiong
Tao Jiang
Shihong Li
Xin Wang
Jing Guo
Si Zhang
Taoyuan Yin
Ting He
Dan Ke
Ruining Li
Honglian Li
Gongping Liu
Xifei Yang
Min–Hua Luo
Xiaohui Zhang
Ying Yang
Jian–Zhi Wang
author_sort Guilin Pi
title Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect
title_short Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect
title_full Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect
title_fullStr Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect
title_full_unstemmed Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect
title_sort posterior basolateral amygdala to ventral hippocampal ca1 drives approach behaviour to exert an anxiolytic effect
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c8dce64f4e8c49f1836109d3e2d14530
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