Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect
Projections from the anterior and posterior basolateral amygdala (pBLA) to the ventral hippocampus CA1 (vCA1) are heterogenous. Here the authors show that activating the pathway from pBLA to vCA1 calbindin 1 positive neurons has an anxiolytic effect in approach-avoidance tasks in mice.
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Nature Portfolio
2020
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oai:doaj.org-article:c8dce64f4e8c49f1836109d3e2d145302021-12-02T14:41:27ZPosterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect10.1038/s41467-019-13919-32041-1723https://doaj.org/article/c8dce64f4e8c49f1836109d3e2d145302020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13919-3https://doaj.org/toc/2041-1723Projections from the anterior and posterior basolateral amygdala (pBLA) to the ventral hippocampus CA1 (vCA1) are heterogenous. Here the authors show that activating the pathway from pBLA to vCA1 calbindin 1 positive neurons has an anxiolytic effect in approach-avoidance tasks in mice.Guilin PiDi GaoDongqin WuYali WangHuiyang LeiWenbo ZengYang GaoHuiling YuRui XiongTao JiangShihong LiXin WangJing GuoSi ZhangTaoyuan YinTing HeDan KeRuining LiHonglian LiGongping LiuXifei YangMin–Hua LuoXiaohui ZhangYing YangJian–Zhi WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
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Science Q Guilin Pi Di Gao Dongqin Wu Yali Wang Huiyang Lei Wenbo Zeng Yang Gao Huiling Yu Rui Xiong Tao Jiang Shihong Li Xin Wang Jing Guo Si Zhang Taoyuan Yin Ting He Dan Ke Ruining Li Honglian Li Gongping Liu Xifei Yang Min–Hua Luo Xiaohui Zhang Ying Yang Jian–Zhi Wang Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect |
description |
Projections from the anterior and posterior basolateral amygdala (pBLA) to the ventral hippocampus CA1 (vCA1) are heterogenous. Here the authors show that activating the pathway from pBLA to vCA1 calbindin 1 positive neurons has an anxiolytic effect in approach-avoidance tasks in mice. |
format |
article |
author |
Guilin Pi Di Gao Dongqin Wu Yali Wang Huiyang Lei Wenbo Zeng Yang Gao Huiling Yu Rui Xiong Tao Jiang Shihong Li Xin Wang Jing Guo Si Zhang Taoyuan Yin Ting He Dan Ke Ruining Li Honglian Li Gongping Liu Xifei Yang Min–Hua Luo Xiaohui Zhang Ying Yang Jian–Zhi Wang |
author_facet |
Guilin Pi Di Gao Dongqin Wu Yali Wang Huiyang Lei Wenbo Zeng Yang Gao Huiling Yu Rui Xiong Tao Jiang Shihong Li Xin Wang Jing Guo Si Zhang Taoyuan Yin Ting He Dan Ke Ruining Li Honglian Li Gongping Liu Xifei Yang Min–Hua Luo Xiaohui Zhang Ying Yang Jian–Zhi Wang |
author_sort |
Guilin Pi |
title |
Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect |
title_short |
Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect |
title_full |
Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect |
title_fullStr |
Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect |
title_full_unstemmed |
Posterior basolateral amygdala to ventral hippocampal CA1 drives approach behaviour to exert an anxiolytic effect |
title_sort |
posterior basolateral amygdala to ventral hippocampal ca1 drives approach behaviour to exert an anxiolytic effect |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/c8dce64f4e8c49f1836109d3e2d14530 |
work_keys_str_mv |
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