Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments

Pandemic of coronavirus disease (COVID-19) is still pressing the healthcare systems worldwide. Thus far, the lack of available COVID-19-targeted treatments has led scientists to look through drug repositioning practices and exploitation of available scientific evidence for potential efficient drugs...

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Autores principales: Marios Spanakis, Athina Patelarou, Evridiki Patelarou, Nikolaos Tzanakis
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Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/c8e11f03c1724e42be50bdc78ade76c4
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spelling oai:doaj.org-article:c8e11f03c1724e42be50bdc78ade76c42021-11-11T16:47:08ZDrug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments10.3390/ijerph1821117111660-46011661-7827https://doaj.org/article/c8e11f03c1724e42be50bdc78ade76c42021-11-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/21/11711https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601Pandemic of coronavirus disease (COVID-19) is still pressing the healthcare systems worldwide. Thus far, the lack of available COVID-19-targeted treatments has led scientists to look through drug repositioning practices and exploitation of available scientific evidence for potential efficient drugs that may block biological pathways of SARS-CoV-2. Till today, several molecules have emerged as promising pharmacological agents, and more than a few medication protocols are applied during hospitalization. On the other hand, given the criticality of the disease, it is important for healthcare providers, especially those in COVID-19 clinics (i.e., nursing personnel and treating physicians), to recognize potential drug interactions that may lead to adverse drug reactions that may negatively impact the therapeutic outcome. In this review, focusing on patients with respiratory diseases (i.e., asthma or chronic obstructive pulmonary disease) that are treated also for COVID-19, we discuss possible drug interactions, their underlying pharmacological mechanisms, and possible clinical signs that healthcare providers in COVID-19 clinics may need to acknowledge as adverse drug reactions due to drug-drug interactions.Marios SpanakisAthina PatelarouEvridiki PatelarouNikolaos TzanakisMDPI AGarticledrug-drug interactionsCOVID-19ADRshealthcare personnelnursing personnelrespiratory diseasesMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 11711, p 11711 (2021)
institution DOAJ
collection DOAJ
language EN
topic drug-drug interactions
COVID-19
ADRs
healthcare personnel
nursing personnel
respiratory diseases
Medicine
R
spellingShingle drug-drug interactions
COVID-19
ADRs
healthcare personnel
nursing personnel
respiratory diseases
Medicine
R
Marios Spanakis
Athina Patelarou
Evridiki Patelarou
Nikolaos Tzanakis
Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments
description Pandemic of coronavirus disease (COVID-19) is still pressing the healthcare systems worldwide. Thus far, the lack of available COVID-19-targeted treatments has led scientists to look through drug repositioning practices and exploitation of available scientific evidence for potential efficient drugs that may block biological pathways of SARS-CoV-2. Till today, several molecules have emerged as promising pharmacological agents, and more than a few medication protocols are applied during hospitalization. On the other hand, given the criticality of the disease, it is important for healthcare providers, especially those in COVID-19 clinics (i.e., nursing personnel and treating physicians), to recognize potential drug interactions that may lead to adverse drug reactions that may negatively impact the therapeutic outcome. In this review, focusing on patients with respiratory diseases (i.e., asthma or chronic obstructive pulmonary disease) that are treated also for COVID-19, we discuss possible drug interactions, their underlying pharmacological mechanisms, and possible clinical signs that healthcare providers in COVID-19 clinics may need to acknowledge as adverse drug reactions due to drug-drug interactions.
format article
author Marios Spanakis
Athina Patelarou
Evridiki Patelarou
Nikolaos Tzanakis
author_facet Marios Spanakis
Athina Patelarou
Evridiki Patelarou
Nikolaos Tzanakis
author_sort Marios Spanakis
title Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments
title_short Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments
title_full Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments
title_fullStr Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments
title_full_unstemmed Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments
title_sort drug interactions for patients with respiratory diseases receiving covid-19 emerged treatments
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/c8e11f03c1724e42be50bdc78ade76c4
work_keys_str_mv AT mariosspanakis druginteractionsforpatientswithrespiratorydiseasesreceivingcovid19emergedtreatments
AT athinapatelarou druginteractionsforpatientswithrespiratorydiseasesreceivingcovid19emergedtreatments
AT evridikipatelarou druginteractionsforpatientswithrespiratorydiseasesreceivingcovid19emergedtreatments
AT nikolaostzanakis druginteractionsforpatientswithrespiratorydiseasesreceivingcovid19emergedtreatments
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